Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

1134233

USP

Citalopram hydrobromide

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile hydrobromide

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C20H21FN2O · HBr
Número de CAS:
59729-32-7
Peso molecular:
405.30
MDL number:
MFCD02101306
UNSPSC Code:
41116107
PubChem Substance ID:
329749406
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

citalopram

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Br[H].CN(C)CCCC1(OCc2cc(ccc12)C#N)c3ccc(F)cc3

InChI

1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H

InChI key

WIHMBLDNRMIGDW-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Citalopram hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Citalopram Oral Solution
  • Citalopram Tablets
  • Escitalopram Tablets

Biochem/physiol Actions

Potent and selective serotonin uptake inhibitor (Ki = 5.4 nM); antidepressant

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

1134244

Citalopram Related Compound A, United States Pharmacopeia (USP) Reference Standard

1134222

Citalopram Related Compound H, United States Pharmacopeia (USP) Reference Standard

1134197

Citalopram Related Compound G, United States Pharmacopeia (USP) Reference Standard

1134288

Citalopram Related Compound E, United States Pharmacopeia (USP) Reference Standard

1134266

Citalopram Related Compound C, United States Pharmacopeia (USP) Reference Standard

1134255

Citalopram Related Compound B, United States Pharmacopeia (USP) Reference Standard

1134277

Citalopram Related Compound D, United States Pharmacopeia (USP) Reference Standard

1134299

Citalopram Related Compound F, United States Pharmacopeia (USP) Reference Standard

Y0000855

Citalopram for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001008

Citalopram hydrobromide, European Pharmacopoeia (EP) Reference Standard

Y0001007

Citalopram hydrochloride, European Pharmacopoeia (EP) Reference Standard

1134142

R-Citalopram oxalate, United States Pharmacopeia (USP) Reference Standard

PHR1906

Citalopram Related Compound H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1863

Citalopram Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1902

Citalopram Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1904

Citalopram Related Compound E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1903

Citalopram Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

BP1153

Citalopram hydrobromide, British Pharmacopoeia (BP) Reference Standard

PHR1905

Citalopram Related Compound G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1901

Citalopram Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

BP1154

Citalopram impurity standard, British Pharmacopoeia (BP) Reference Standard

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Gordon F Buchanan et al.
The Journal of physiology, 592(19), 4395-4410 (2014-08-12)
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy. Defects in central control of breathing are important contributors to the pathophysiology of SUDEP, and serotonin (5-HT) system dysfunction may be involved. Here
Yevheniia Mikheenko et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(6), 1395-1404 (2015-01-15)
Trait anxiety is a risk factor for the development and maintenance of affective disorders, and insights into the underlying brain mechanisms are vital for improving treatment and prevention strategies. Translational studies in non-human primates, where targeted neurochemical and genetic manipulations
M D Opal et al.
Molecular psychiatry, 19(10), 1106-1114 (2013-10-30)
Current antidepressants must be administered for several weeks to produce therapeutic effects. We show that selective serotonin 2C (5-HT2C) antagonists exert antidepressant actions with a faster-onset (5 days) than that of current antidepressants (14 days) in mice. Subchronic (5 days)
Mark R Davies et al.
Cell reports. Medicine, 1(5), 100076-100076 (2020-11-19)
There is an increasing expectation that computational approaches may supplement existing human decision-making. Frontloading of models for cardiac safety prediction is no exception to this trend, and ongoing regulatory initiatives propose use of high-throughput in vitro data combined with computational models
Jesper T Andreasen et al.
Brain research, 1601, 117-126 (2015-01-13)
Depression and anxiety often co-occur, and conventional monoamine-facilitating antidepressants show efficacy against symptoms in both disorders. Rodent studies indicate that antidepressant effects of monoamine-based antidepressants involve increased α-amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid glutamate receptor (AMPAR) neurotransmission, and positive allosteric modulators (PAMs) at
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico