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Merck

84110

Sigma-Aldrich

Sucrose monolaurate

BioXtra, ≥97.0% (TLC)

Sinónimos:

n-Dodecanoylsucrose, Lauric acid sucrose ester, Sucrose monododecanoate

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About This Item

Fórmula empírica (notación de Hill):
C24H44O12
Número de CAS:
Peso molecular:
524.60
Beilstein/REAXYS Number:
65819
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

product line

BioXtra

assay

≥97.0% (TLC)

form

powder

mol wt

524.60 g/mol

impurities

≤3% water

CMC

0.3

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC(=O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C24H44O12/c1-2-3-4-5-6-7-8-9-10-11-17(27)33-13-16-18(28)20(30)21(31)23(34-16)36-24(14-26)22(32)19(29)15(12-25)35-24/h15-16,18-23,25-26,28-32H,2-14H2,1H3/t15-,16-,18-,19-,20+,21-,22+,23-,24+/m1/s1

InChI key

KGUHOFWIXKIURA-VQXBOQCVSA-N

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General description

Sucrose monolaurate is a non-ionic detergent and a carbohydrate fatty acid monoester. It is generally used for the solubilization of membrane proteins.

Application

Sucrose monolaurate has been used as an antimicrobial agent. It has also been used as a constituent of lysis buffer to homogenize placental tissues for determining serine palmitoyltransferase (SPT) activity.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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Levente Kürti et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(3), 445-454 (2012-01-26)
Sucrose esters are effective solubilizers and there is an interest to use them as pharmaceutical excipients for nasal drug delivery. We have determined for the first time the non-toxic doses of laurate and myristate sucrose esters by four independent methods
Angéla Szuts et al.
International journal of pharmaceutics, 410(1-2), 107-110 (2011-03-23)
This study focused on an investigation of the applicability of sucrose laurate as surfactant in solid dispersions. Although this surfactant has a US Drug Master File, it has not been used so far in internal pharmaceutical products. High drug-loaded solid
Shan He et al.
PloS one, 14(5), e0216816-e0216816 (2019-05-31)
The high heat and mass transfer, and controlled mechanoenergy, in angled vortex fluidics has been applied in chemical and material sciences and allied fields, but its utility in food processing remains largely unexplored. Herein we report three models of food
Prediction of Listeria monocytogenes ATCC 7644 growth on fresh-cut produce treated with bacteriophage and sucrose monolaurate by using artificial neural network
Oladunjoye A, et al.
LWT--Food Science and Technology, 76, 9-17 (2017)
Christopher Rupp et al.
International journal of pharmaceutics, 395(1-2), 272-280 (2010-06-29)
A remarkable part of newly developed active pharmaceutical ingredients is rejected in early phase development and will never find a way to a patient because of poor water solubility which is often paired with poor bioavailability. Considering such arising solubility

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