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PHR1050

Supelco

Benzoic acid

Pharmaceutical Secondary Standard; Certified Reference Material

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About This Item

Fórmula lineal:
C6H5COOH
Número de CAS:
65-85-0
Peso molecular:
122.12
Beilstein/REAXYS Number:
636131
EC Number:
200-618-2
MDL number:
MFCD00002398
UNSPSC Code:
41116107
eCl@ss:
39023903
PubChem Substance ID:
329823080
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to USP 1055002

vapor density

4.21 (vs air)

vapor pressure

10 mmHg ( 132 °C)

description

API family: benfluorex

API family

metronidazole, benfluorex, mefenamic acid

CofA

current certificate can be downloaded

autoignition temp.

1061 °F

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

249 °C (lit.)

mp

121-125 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)c1ccccc1

InChI

1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)

InChI key

WPYMKLBDIGXBTP-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Benzoic acid may be used as a reference standard in determining the concentration of benzoic acid in food and milk samples using high performance liquid chromatography coupled with photodiode array detector (HPLC).[1][2]

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB8257 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

related product

Referencia del producto
Descripción
Precios

PHR1052

Metronidazole, Pharmaceutical Secondary Standard; Certified Reference Material

1055002

Benzoic acid, United States Pharmacopeia (USP) Reference Standard

Y0000087

Metronidazole impurity A, European Pharmacopoeia (EP) Reference Standard

M0252600

Mefenamic acid, European Pharmacopoeia (EP) Reference Standard

M1850000

Metronidazole, European Pharmacopoeia (EP) Reference Standard

M1851000

Metronidazole benzoate, European Pharmacopoeia (EP) Reference Standard

Y0001081

Mefenamic acid impurity A, European Pharmacopoeia (EP) Reference Standard

Y0001470

Benzoic acid, European Pharmacopoeia (EP) Reference Standard

1442009

Metronidazole, United States Pharmacopeia (USP) Reference Standard

1379605

Mefenamic acid, United States Pharmacopeia (USP) Reference Standard

1442100

Metronidazole benzoate, United States Pharmacopeia (USP) Reference Standard

1211254

2,3-Dimethylaniline, United States Pharmacopeia (USP) Reference Standard

BP603

Metronidazole, British Pharmacopoeia (BP) Reference Standard

BP244

2-Methyl-5-nitroimidazole, British Pharmacopoeia (BP) Reference Standard

BP735

Metronidazole benzoate, British Pharmacopoeia (BP) Reference Standard

PHR2165

Metronidazole Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2514

Metronidazole Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2512

Metronidazole Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation

target_organs

Lungs

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Determination of benzoic and sorbic acids in Brazilian food
Tfouni.V.A.S and Toledo F.C.M
Food Control, 13, 117-123 (2002)
Determination of benzoic and sorbic acids in Brazilian food
Qi P, et al.
Food Control, 20, 414-418 (2009)
Renbo Wei et al.
Macromolecular rapid communications, 34(4), 330-334 (2013-01-03)
A new approach is developed to fabricate highly oriented mono-domain LCE nano/microstructures through micro-molding in capillaries. Gratings and microwires as two typical examples are fabricated and characterized by polarizing optical microscopy, optical microscopy, and scanning electron microscopy. The gratings with
S Nacht et al.
Journal of the American Academy of Dermatology, 4(1), 31-37 (1981-01-01)
The transepidermal penetration and metabolic disposition of 14C-benzoyl peroxide were assessed in vitro (excised human skin) and in vivo (rhesus monkey). In vitro, the benzoyl peroxide penetrated into the skin, through the stratum corneum or the follicular openings, or both
Ly Dieu Tran et al.
Journal of the American Chemical Society, 134(44), 18237-18240 (2012-10-30)
An auxiliary-assisted, copper catalyzed or promoted sulfenylation of benzoic acid derivative β-C-H bonds and benzylamine derivative γ-C-H bonds has been developed. The method employs disulfide reagents, copper(II) acetate, and DMSO solvent at 90-130 °C. Application of this methodology to the
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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