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Y0000087

Metronidazole impurity A

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

2-Methyl-4(5)-nitroimidazole

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About This Item

Fórmula empírica (notación de Hill):
C4H5N3O2
Número de CAS:
696-23-1
Peso molecular:
127.10
Beilstein/REAXYS Number:
4032
MDL number:
MFCD00151322
UNSPSC Code:
41116107
PubChem Substance ID:
329830836
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

metronidazole

manufacturer/tradename

EDQM

mp

251-255 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cc1ncc([nH]1)[N+]([O-])=O

InChI

1S/C4H5N3O2/c1-3-5-2-4(6-3)7(8)9/h2H,1H3,(H,5,6)

InChI key

FFYTTYVSDVWNMY-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metronidazole impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

PHR1050

Benzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1052

Metronidazole, Pharmaceutical Secondary Standard; Certified Reference Material

1055002

Benzoic acid, United States Pharmacopeia (USP) Reference Standard

M1850000

Metronidazole, European Pharmacopoeia (EP) Reference Standard

M1851000

Metronidazole benzoate, European Pharmacopoeia (EP) Reference Standard

Y0001470

Benzoic acid, European Pharmacopoeia (EP) Reference Standard

1442009

Metronidazole, United States Pharmacopeia (USP) Reference Standard

1442100

Metronidazole benzoate, United States Pharmacopeia (USP) Reference Standard

BP603

Metronidazole, British Pharmacopoeia (BP) Reference Standard

BP244

2-Methyl-5-nitroimidazole, British Pharmacopoeia (BP) Reference Standard

BP735

Metronidazole benzoate, British Pharmacopoeia (BP) Reference Standard

PHR2165

Metronidazole Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2514

Metronidazole Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2512

Metronidazole Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Daniel D Rossouw et al.
Nuclear medicine and biology, 32(4), 385-394 (2005-05-10)
The inflammation- and infection-seeking properties of (131)I-labeled ornidazole, a 5-nitroimidazole derivative, have recently been reported. Whole-body images in rabbits showed a more rapid uptake in inflamed areas compared to (67)Ga. In the present study, two novel (123)I-labeled 2-methyl-4-nitroimidazole derivatives were
Fa-qing Ye et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 38(4), 260-263 (2003-08-02)
To study the synthesis and antibacterial activity of pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol. Pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol were synthesized primarily from 2-methyl-5-nitroimidazol, norfloxacin, ciprofloxacin, enoxacin via nucleophilic substitution and esterification. The antibacterial activity of the nine target compounds were
G Carignan et al.
Food additives and contaminants, 8(4), 467-475 (1991-07-01)
An unidentified metabolite of dimetridazole (DMZ), found in pig plasma, muscle and kidney, was shown by chromatography and spectroscopy to be 2-methyl-5-nitroimidazole (2-MNI), resulting from N-demethylation of DMZ. This route of degradation competes with the oxidation pathway previously described. The
Madhava B Mallia et al.
Bioorganic & medicinal chemistry, 14(23), 7666-7670 (2006-09-05)
An iminodiacetic acid (IDA) derivative of 2-methyl-5-nitroimidazole was synthesized as a carrier molecule for radiolabeling with the gamma emitting radioisotope, 99mTc, for imaging hypoxic regions of tumors. The ligand was synthesized in excellent yield and labeled using freshly prepared [99mTc(CO)3(H2O)3]+
Fa-qing Ye et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 40(2), 132-135 (2005-05-07)
To study the synthesis and antibacterial activity of ciprofloxacin derivatives. Ciprofloxacin derivatives were synthesized primarily from 2-methyl-5-nitroimidazol and ciprofloxacin through nucleophilic substitution. The antibacterial activity of the synthesized compounds were tested. Nine new compounds were synthesized. The structure of the
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