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34001

Supelco

Ceftiofur

VETRANAL®, analytical standard

Sinónimos:

3-[(2-Furylcarbonyl)thio]methyl]-7-[2-(2-amino-4-thiazolyl)-2-(methoxyiminoacetamido)-3-cephem-4-carboxylic acid

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About This Item

Fórmula empírica (notación de Hill):
C19H17N5O7S3
Número de CAS:
80370-57-6
Peso molecular:
523.56
MDL number:
MFCD00864953
UNSPSC Code:
41116107
PubChem Substance ID:
329754745
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

CO\N=C(/C(=O)N[C@H]1C2SCC(CSC(=O)c3ccco3)=C(N2C1=O)C(O)=O)c4csc(N)n4

InChI

1S/C19H17N5O7S3/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28)/b23-11-/t12-,16?/m1/s1

InChI key

ZBHXIWJRIFEVQY-FITYNHDMSA-N

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General description

Ceftiofur is a third-generation cephalosporin antibiotic, which is commonly used in veterinary medicine for the treatment of respiratory diseases and bacterial infections in farm animals.

Application

Ceftiofur has been used as an analytical reference standard for the determination of the analyte in:
  • Milk samples using receptor binding assays such as Betastar Combo, SNAP, and Twinsensor tests.
  • Environmental water samples using capillary electrophoresis.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCK8841
BCCD2522
BCBS8768V
BCBS8758V
SZBF222XV

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Visite la Librería de documentos

Improving the sensitivity of the determination of ceftiofur by capillary electrophoresis in environmental water samples: In-line solid phase extraction and sample stacking techniques.
Puig P, et al.
Analytica Chimica Acta, 587(2), 208-215 (2007)
Rex E Hornish et al.
Current topics in medicinal chemistry, 2(7), 717-731 (2002-06-08)
Cephalosporins are an important class of antibacterial agents in use today for both humans and animals. Four generations of cephalosporins have evolved, all of which contain the beta-lactam sub-structure first found in penicillin. The range of cephalosporins available for use
Determination of ceftiofur and its metabolite desfuroylceftiofur in bovine serum and milk by ion-paired liquid chromatography.
Tyczkowska LK, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 614(1), 123-134 (1993)
Validation of receptor-binding assays to detect antibiotics in goat's milk.
Beltran CM, et al.
Journal of Food Protection, 77(2), 308-313 (2014)
Sanjie Caol et al.
BMC veterinary research, 13(1), 293-293 (2017-10-01)
Lyme disease in humans is predominantly treated with tetracycline, macrolides or beta lactam antibiotics that have low minimum inhibitory concentrations (MIC) against Borrelia burgdorferi. Horses with Lyme disease may require long-term treatment making frequent intravenous or intramuscular treatment difficult and
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