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Key Documents

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09415

Sigma-Aldrich

Sodium 4-aminosalicylate dihydrate

≥97.0% (T)

Sinónimos:

4-Amino-2-hydroxybenzoic acid sodium salt, 4-Amino-salicylic acid sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C7H6NNaO3 · 2H2O
Número de CAS:
6018-19-5
Peso molecular:
211.15
EC Number:
205-091-2
MDL number:
MFCD00151044
UNSPSC Code:
41116107
PubChem Substance ID:
329748763
NACRES:
NA.22

Quality Level

200

assay

≥97.0% (T)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

ligand binding assay: suitable

color

white to faintly beige

application(s)

peptide synthesis

SMILES string

O.O.[Na+].Nc1ccc(c(O)c1)C([O-])=O

InChI

1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H,10,11);;2*1H2/q;+1;;/p-1

InChI key

GMUQJDAYXZXBOT-UHFFFAOYSA-M

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0001257115
1257115
1140896
1257115V
453791/1

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V E Sagynbaeva et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (3)(3), 40-46 (2012-07-27)
Detection of IgM and IgG Chlamydia and Mycoplasma pneumoniae indicates an aggravation of intracellular infections, including, possibly, due to immunosuppressive therapy. It is possible that the intracellular infection may mediate the occurrence of certain extraintestinal manifestations of inflammatory bowel disease
Shuichi Yano et al.
BMJ case reports, 2012, doi:10-doi:10 (2012-05-19)
Isoniazid (H) or rifampicin (R) mono-resistant disease can be treated easily and effectively with first-line drugs, while combined H and R resistance (ie, multidrug-resistant tuberculosis (MDRTB)) requires treatment with at least four agents, including a quinolone and an injectable agent.
[A chronic moderate manganism poisoning treated with sodium p-aminosalicylic acid].
Wei-Ping Qin et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29(8), 619-620 (2012-02-18)
S M Vesenbeckh et al.
Infection, 40(2), 199-202 (2011-08-13)
para-Aminosalicylic acid (PAS) is commonly used in the treatment of drug-resistant tuberculosis, including multidrug-resistant tuberculosis. Since its first use in the 1940s, hypersensitivity reactions frequently limit its use in clinical practice. Cases of successful desensitization against PAS using orally administered
Lan Hong et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(10), 1904-1909 (2011-07-20)
para-aminosalicylic acid (PAS; 4-amino-2-hydroxybenzoic acid), an antituberculosis drug in use since the 1950s, has recently been suggested to be an effective agent for treatment of manganese-induced parkinsonian disorders. However, the neuropharmacokinetics of PAS and its metabolite N-acetyl-para-aminosalicylic acid (AcPAS; N-acetyl-4-amino-2-hydroxybenzoic
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