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Merck

131377

Sigma-Aldrich

1,10-Phenanthroline

≥99%

Sinónimos:

o-phenanthroline

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About This Item

Fórmula empírica (notación de Hill):
C12H8N2
Número de CAS:
Peso molecular:
180.21
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39210124
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥99%

form

powder

mp

114-117 °C (lit.)

SMILES string

c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H

InChI key

DGEZNRSVGBDHLK-UHFFFAOYSA-N

Gene Information

human ... FNTA(2339)

Application

1,10-Phenanthroline can be used as:
  • A cathode buffer layer to improve the efficiency of organic solar cells.
  • A conventional chelator to study its efficacy in Fenton′s reaction-luminol chemiluminescence system.
  • A ligand in mild, copper (II)-catalyzed cross-coupling of organoboronic acids and sulfinate salts, leading to aryl- and alkenylsulfones.
  • A versatile ligand employed in the spectrophotometric determination of metals and photocatalytic reduction of carbon dioxide.
  • A building block for metallomacrocycles.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Mitsuhiro Wada et al.
Luminescence : the journal of biological and chemical luminescence, 29(7), 955-958 (2014-01-10)
In vitro screening of a Fe(2+) -chelating effect using a Fenton's reaction-luminol chemiluminescence (CL) system is described. The luminescence between the reactive oxygen species generated by the Fenton's reaction and luminol was decreased on capturing Fe(2+) using a chelator. The
Catalysis by Metal Complexes, 14, 217-217 (1993)
Neville S Ng et al.
Dalton transactions (Cambridge, England : 2003), 42(9), 3196-3209 (2012-12-13)
Copper(II) (1(Cu)-21(Cu)) and previously established experimental anticancer platinum(II) metallointercalator complexes (1(Pt)-16(Pt)) have been prepared and investigated for their antimicrobial properties. These complexes are of the general structure [M(I(L))(A(L))](2+) where I(L) represents functionalised 1,10-phenanthrolines (1(IL)-10(IL)), and A(L) represents 1,2-diaminoethane, 1S,2S- or
Aswan Sci. Technol. Bull., 13, 3-3 (1992)
Daisuke Nishimiya et al.
Scientific reports, 9(1), 11436-11436 (2019-08-09)
Proteases are one of attractive therapeutic targets to play key roles in pharmacological action. There are many protease inhibitors in nature, and most of them structurally have cystine knot motifs. Their structures are favorable for recognition of active pockets of

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