745774
8-Amino-1-octanethiol hydrochloride
95%
Sinónimos:
8-Mercaptooctylamine hydrochloride
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About This Item
Productos recomendados
Quality Level
assay
95%
form
solid
mp
158-163 °C
storage temp.
2-8°C
SMILES string
SCCCCCCCCN.Cl
InChI
1S/C8H19NS.ClH/c9-7-5-3-1-2-4-6-8-10;/h10H,1-9H2;1H
InChI key
CCWZBRKMJBSNQS-UHFFFAOYSA-N
Categorías relacionadas
General description
8-Amino-1-octanethiol hydrochloride (8-AOT) is an amine based alkanethiol that can be used as a self-assembled monolayer (SAM) on a variety of surfaces. It facilitates the immobilization of surface atoms and controls the physiochemical properties of the substrate.
Application
8-AOT can be used in the surface functionalization of gold electrodes for the trace analysis of oligonucleotide using poly nucleic acid (PNA) based ion-channel sensors. It can be used in the fabrication of peptide microarray for surface plasmon resonance based screening of protein kinase activity.
Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Los clientes también vieron
Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging
Analytical Biochemistry, 375(2), 223-231 (2008)
Photooxidation of amine-terminated self-assembled monolayers on gold
The Journal of Physical Chemistry C, 114(23), 10512-10519 (2010)
Trace analysis of an oligonucleotide with a specific sequence using PNA-based ion-channel sensors
Analyst, 128(6), 681-685 (2003)
Tuning the surface potential of gold substrates arbitrarily with self-assembled monolayers with mixed functional groups
Physical Chemistry Chemical Physics, 11(29), 6199-6204 (2009)
ACS nano, 5(10), 7722-7729 (2011-09-09)
A high-affinity RNA aptamer (K(d) = 50 nM) was efficiently identified by SELEX against a heteroaryldihydropyrimidine structure, chosen as a representative drug-like molecule with no cross reactivity with mammalian or bacterial cells. This aptamer, its weaker-binding variants, and a known
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