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725986

Sigma-Aldrich

Trimethylsilanol

≥97.5% (GC)

Sinónimos:

TMS, TMSiOH, Hydroxytrimethylsilane

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About This Item

Fórmula lineal:
(CH3)3SiOH
Número de CAS:
1066-40-6
Peso molecular:
90.20
Beilstein:
1361356
Número CE:
213-914-1
Número MDL:
MFCD02751657
Código UNSPSC:
12352103
ID de la sustancia en PubChem:
329764205
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nivel de calidad

100

Ensayo

≥97.5% (GC)

Formulario

liquid

cadena SMILES

C[Si](C)(C)O

InChI

1S/C3H10OSi/c1-5(2,3)4/h4H,1-3H3

Clave InChI

AAPLIUHOKVUFCC-UHFFFAOYSA-N

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Aplicación

Trimethylsilanol (TMS) can be used to prepare tris(trimethylsiloxy) aluminum (I) by reacting with triethylaluminum.[1]

Pictogramas

FlameExclamation mark
GHS02,GHS07

Palabra de señalización

Danger

Frases de peligro

H225,H332,H412

Clasificaciones de peligro

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Flam. Liq. 2

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

44.6 °F - closed cup

Punto de inflamabilidad (°C)

7 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number
BCCM5455
BCCL5685
BCCL8554
BCCK9204
BCCK0035

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Joan Malmstrøm
Journal of pharmaceutical sciences, 108(4), 1512-1520 (2018-11-25)
During the past years, there has been an increasing focus on the presence of silicone oil as a contaminant in pharmaceutical formulations kept in prefilled syringes (PFSs). As the PFSs are coated on the inner wall with silicone oil (polydimethylsiloxane)
Reactions of Aldehyde Caused by Tris (trimethylsiloxy) aluminum.
Saegusa T, et al.
Bulletin of the Chemical Society of Japan, 40(8), 1960-1964 (1967)
Xiao-Meng Chong et al.
Drug development and industrial pharmacy, 45(1), 159-167 (2018-09-21)
Establish an effective experimental strategy to determine the compatibility of rubber closures for drugs. Various types of rubber closures with different compositions are available for drug packaging. Many additives of rubber closures can be released from rubber closures and may
Grzegorz Piechota et al.
Bioresource technology, 103(1), 16-20 (2011-10-29)
The removal and determination of trimethylsilanol (TMSOH) in landfill gas has been studied before and after the special E3000-ITC System. The system works according to principle of temperature swing. The performance of TMSOH and humidity removal was 20% and more
A Isquith et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 26(3), 263-266 (1988-03-01)
Six organosilicon compounds which had been found to have clastogenic activity in an in vitro battery of genotoxicity assays were evaluated in rat bone marrow cytogenetic assays for assessing clastogenicity in an in vivo system. None of the six compounds
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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