474789

(S)-(−)-Glycidol

97%, optical purity ee: 98% (GLC)

• Sinónimos: (S)-(−)-2,3-Epoxy-1-propanol, (S)-(−)-Oxirane-2-methanol
• Fórmula empírica (notación de Hill): C₃H₆O₂
• Número de CAS: 60456-23-7
• Peso molecular: 74.08
• Beilstein/REAXYS Number: 79783
• MDL number: MFCD00074874
• UNSPSC Code: 12352005
• PubChem Substance ID: 24871051
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 97%
• optical activity: [α]20/D −15°, neat
• optical purity: ee: 98% (GLC)
• refractive index: n20/D 1.433 (lit.)
• bp: 66-67 °C/19 mmHg (lit.)
• density: 1.116 g/mL at 20 °C (lit.)
• functional group: ether; hydroxyl
• storage temp.: −20°C
• SMILES string: OC[C@H]1CO1
• InChI: 1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2/t3-/m0/s1
• InChI key: CTKINSOISVBQLD-VKHMYHEASA-N

Descripción

General description

Glycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters, polycarbonates, polyurethanes, and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.

Application

Employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302 + H312,H315,H319,H330,H335,H341,H350,H360F
• pcodes: P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 161.6 °F
• flash_point_c: 72 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter