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288225

Sigma-Aldrich

Chloro(triethylphosphine)gold(I)

97%

Sinónimos:

(Triethylphosphine)gold(I) chloride

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About This Item

Fórmula lineal:
(C2H5)3PAuCl
Número de CAS:
15529-90-5
Peso molecular:
350.58
EC Number:
239-572-3
MDL number:
MFCD00013205
UNSPSC Code:
12161600
PubChem Substance ID:
24857327
NACRES:
NA.22

Quality Level

100

assay

97%

form

solid

reaction suitability

core: gold
reagent type: catalyst

bp

210 °C/0.03 mmHg (lit.)

mp

84-86 °C (lit.)

SMILES string

Cl[Au].CCP(CC)CC

InChI

1S/C6H15P.Au.ClH/c1-4-7(5-2)6-3;;/h4-6H2,1-3H3;;1H/q;+1;/p-1

InChI key

SYBBXLKWGHAVHP-UHFFFAOYSA-M

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
SHBN0586
SHBJ6628
SHBH1081V
SHBF4326V
SHBC6599V

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A A Isab et al.
Journal of inorganic biochemistry, 38(2), 95-100 (1990-02-01)
New compounds having the formula [L-Au-PEt3]Cl (where L = imidazolidine-2-thione(Imt) and 1,3-Diazinane-2-thione(Diaz)) are synthesized. They are characterized by elemental analysis, infrared, 13C and 31P NMR spectroscopy.
G F Rush et al.
Toxicology and applied pharmacology, 90(3), 377-390 (1987-09-30)
Triethylphosphine gold complexes are effective therapeutic agents used for the treatment of rheumatoid arthritis. Many of those molecules are also highly cytotoxic in vitro and can inhibit DNA and protein synthesis. Preliminary experiments have indicated that triethylphosphine gold chloride (TEPAu)
The comparative toxicity of gold salts.
B J Payne
The Journal of rheumatology. Supplement, 8, 79-80 (1982-07-01)
C E Blank et al.
Journal of inorganic biochemistry, 21(1), 21-29 (1984-05-01)
The DNA binding properties of the Au(I)-containing antiarthritic drug Ridaura and related Au(I) complexes have been investigated. Absorption and circular dichroism spectroscopy show that if the gold ion possesses an easily displaced ligand, e.g., Cl- or Br-, Au(I) is capable
G D Hoke et al.
Toxicology and applied pharmacology, 99(1), 50-60 (1989-06-01)
Chlorotriethylphosphine gold(I) (TEPAu) is an organo-gold compound that has therapeutic activity in animal models of rheumatoid arthritis. Initial studies have suggested that TEPAu is a potent cytotoxic compound in vitro against a variety of cultured cell types and isolated hepatocytes.
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