195650

2-Nitroimidazole

98%

• Sinónimos: Azomycin
• Fórmula empírica (notación de Hill): C₃H₃N₃O₂
• Número de CAS: 527-73-1
• Peso molecular: 113.07
• Beilstein/REAXYS Number: 116444
• EC Number: 208-425-5
• MDL number: MFCD00005185
• UNSPSC Code: 12352005
• PubChem Substance ID: 24851703
• NACRES: NA.22

Propiedades

• assay: 98%
• form: solid
• mp: 287 °C (dec.) (lit.)
• functional group: nitro
• SMILES string: [O-][N+](=O)c1ncc[nH]1
• InChI: 1S/C3H3N3O2/c7-6(8)3-4-1-2-5-3/h1-2H,(H,4,5)
• InChI key: YZEUHQHUFTYLPH-UHFFFAOYSA-N

Descripción

General description

2-Nitroimidazole is a natural antibiotic.

Application

2-Nitroimidazole was used in the synthesis of:

• tert-butyl 2-(2-nitro-1H-imidazol-1-yl)ethylcarbamate
• 1-(2-(tert-butyldimethylsilyloxy)ethyl)-2-nitro-1H-imidazole
• 2-fluoro-N-(2-(2-nitro-1H-imidazol-1-yl)ethyl)acetamide
• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl 2-fluoroacetate
• radiolabeling precursors - the bromo substituted analogs
• nitroimidazole substituted boronic acids, precursors for imaging hypoxic tissue
• potential site-selective radiosensitizers for estrogen receptor-rich tumors

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

solubility :
50 mg/mL in NH₄OH : soluble, clear, green-yellow, to very dark green-yellow to very dark yellow

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves