47775

Menadione (K3)

analytical standard

• Sinónimos: Menadione
• Fórmula empírica (notación de Hill): C₁₁H₈O₂
• Número de CAS: 58-27-5
• Peso molecular: 172.18
• Beilstein/REAXYS Number: 1908453
• EC Number: 200-372-6
• MDL number: MFCD00001681
• UNSPSC Code: 12164500
• PubChem Substance ID: 24871411

Propiedades

• grade: analytical standard
• CofA: current certificate can be downloaded
• feature: standard type fat soluble vitamin
• packaging: ampule of 1000 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 105-107 °C (lit.)
• application(s): pharmaceutical (small molecule); vitamins, nutraceuticals, and natural products
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• InChI key: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• Gene Information: human ... NQO1(1728)

Descripción

General description

Menadione (K3) is a fat-soluble vitamin precursor and catabolic product of oral phylloquinone (vitamin k1) in the intestine.

Menadione is a prothrombogenic compound and belongs to the Vitamin K class of compounds, which are necessary for the biosynthesis of prothrombin and other blood clotting factors. It is used as a model quinone in cell culture and in vivo investigations. It is obtained as a catabolic product of phylloquinone and circulating precursor of tissue menaquinone-4 in rats.

Application

Menadione (K3) may be used as an analytical reference standard for the quantification of the analyte in biological fluids using liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Información de seguridad

• Pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H317,H319,H335,H410
• pcodes: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves