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Key Documents

S7273

Sigma-Aldrich

Sera from mouse

frozen liquid (from clotted whole blood)

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

biological source

mouse

Quality Level

description

Contains no azides

sterility

sterile; aseptically filled

form

frozen liquid (from clotted whole blood)

origin

USA origin

shipped in

dry ice

storage temp.

−20°C

General description

Mouse serum is used in a variety of mouse cell culture systems to study viral infection, inhibition, and transduction processes.

Application

Sera from mouse has been used:
  • as a source of inter-α-inhibitor (IαI) in protein modification to form the heavy chain (HC)-hyaluronan (HA) complex
  • to culture primary mouse airway smooth muscle cells (MASM) and primary human airway smooth muscle cells (HASM)
  • as analytical quality control (QC) sample for metabolomics analysis of treated mice serum

Suitability

Not tested for use in cell culture

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Mark E Lauer et al.
The Journal of biological chemistry, 288(1), 205-214 (2012-11-21)
The covalent transfer of heavy chains (HCs) from inter-α-inhibitor (IαI) to hyaluronan (HA) via the protein product of tumor necrosis factor-stimulated gene-6 (TSG-6) forms the HC-HA complex, a pathological form of HA that promotes the adhesion of leukocytes to HA
Alexandra E Livanos et al.
Nature microbiology, 1(11), 16140-16140 (2016-10-27)
The early life microbiome plays important roles in host immunological and metabolic development. Because the incidence of type 1 diabetes (T1D) has been increasing substantially in recent decades, we hypothesized that early-life antibiotic use alters gut microbiota, which predisposes to
Sven-Bastiaan Haange et al.
Metabolites, 12(7) (2022-07-28)
Bile acids are a key mediator of the molecular microbiome-host interaction, and various mass spectrometry-based assays have been developed in the recent decade to quantify a wide range of bile acids. We compare existing methodologies to harmonize them. Methodology for
Mark E Lauer et al.
The Journal of biological chemistry, 284(8), 5313-5323 (2008-12-17)
The covalent association of inter-alpha-inhibitor-derived heavy chains (HCs) with hyaluronan was first described in synovial fluid from arthritic patients and later described as a structural and functional component of hyaluronan "cable" structures produced by many different cells and stimuli. HC
Kleopatra Rapti et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 20(1), 73-83 (2011-09-15)
Adeno-associated virus (AAV)-based vectors are promising gene delivery vehicles for human gene transfer. One significant obstacle to AAV-based gene therapy is the high prevalence of neutralizing antibodies in humans. Until now, it was thought that, except for nonhuman primates, pre-existing

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