S7273
Sera from mouse
frozen liquid (from clotted whole blood)
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About This Item
UNSPSC Code:
12352207
NACRES:
NA.71
Productos recomendados
biological source
mouse
Quality Level
description
Contains no azides
sterility
sterile; aseptically filled
form
frozen liquid (from clotted whole blood)
origin
USA origin
shipped in
dry ice
storage temp.
−20°C
General description
Mouse serum is used in a variety of mouse cell culture systems to study viral infection, inhibition, and transduction processes.
Application
Sera from mouse has been used:
- as a source of inter-α-inhibitor (IαI) in protein modification to form the heavy chain (HC)-hyaluronan (HA) complex
- to culture primary mouse airway smooth muscle cells (MASM) and primary human airway smooth muscle cells (HASM)
- as analytical quality control (QC) sample for metabolomics analysis of treated mice serum
Suitability
Not tested for use in cell culture
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Los clientes también vieron
Mark E Lauer et al.
The Journal of biological chemistry, 288(1), 205-214 (2012-11-21)
The covalent transfer of heavy chains (HCs) from inter-α-inhibitor (IαI) to hyaluronan (HA) via the protein product of tumor necrosis factor-stimulated gene-6 (TSG-6) forms the HC-HA complex, a pathological form of HA that promotes the adhesion of leukocytes to HA
Alexandra E Livanos et al.
Nature microbiology, 1(11), 16140-16140 (2016-10-27)
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Mark E Lauer et al.
The Journal of biological chemistry, 284(8), 5313-5323 (2008-12-17)
The covalent association of inter-alpha-inhibitor-derived heavy chains (HCs) with hyaluronan was first described in synovial fluid from arthritic patients and later described as a structural and functional component of hyaluronan "cable" structures produced by many different cells and stimuli. HC
Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models.
Kleopatra Rapti et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 20(1), 73-83 (2011-09-15)
Adeno-associated virus (AAV)-based vectors are promising gene delivery vehicles for human gene transfer. One significant obstacle to AAV-based gene therapy is the high prevalence of neutralizing antibodies in humans. Until now, it was thought that, except for nonhuman primates, pre-existing
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