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M2435

Sigma-Aldrich

c-Myc Peptide

≥97%, lyophilized powder

Sinónimos:

c-Myc tag

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About This Item

MDL number:
MFCD03456424
UNSPSC Code:
12352202
NACRES:
NA.56

product name

c-Myc Peptide, lyophilized powder

biological source

synthetic

Quality Level

200

assay

≥97%

form

lyophilized powder

mol wt

1203.3 Da

concentration

5-10 μg/mL (Suggested working concentration to compete out the binding of c-Myc)

technique(s)

protein extraction: suitable

storage temp.

−20°C

Amino Acid Sequence

Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu

General description

The c-Myc Peptide is a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of the C-terminal of human c-myc.

Application

Useful for displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific.

Other Notes

Amino acid sequence is corresponds to amino acids 410-419 of the C-terminal of human c-Myc.
Lyophilized from 0.1% TFA in H2O

Preparation Note

Dissolve in water to a final concentration of 5 mg/mL.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Yanxiao Zhang et al.
Oncotarget, 8(4), 5761-5773 (2016-12-23)
PAX8-PPARG fusion protein (PPFP) results from a t(2;3)(q13;p25) chromosomal translocation, is found in 30% of follicular thyroid carcinomas, and demonstrates oncogenic capacity in transgenic mice. A PPARG ligand, pioglitazone, is highly therapeutic in mice with PPFP thyroid cancer. However, only
Daria D Korotkova et al.
Cell reports, 29(4), 1027-1040 (2019-10-24)
The molecular basis of higher regenerative capacity of cold-blooded animals comparing to warm-blooded ones is poorly understood. Although this difference in regenerative capacities is commonly thought to be a result of restructuring of the same regulatory gene network, we hypothesized
Atanas G Atanasov et al.
Biochimica et biophysica acta, 1783(8), 1536-1543 (2008-04-03)
Hexose-6-phosphate dehydrogenase (H6PDH) has been shown to stimulate 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-dependent local regeneration of active glucocorticoids. Here, we show that coexpression with H6PDH results in a dramatic shift from 11beta-HSD1 oxidase to reductase activity without affecting the activity
Advait Subramanian et al.
Cell, 176(6), 1461-1476 (2019-03-09)
Maintaining the optimal performance of cell processes and organelles is the task of auto-regulatory systems. Here we describe an auto-regulatory device that helps to maintain homeostasis of the endoplasmic reticulum (ER) by adjusting the secretory flux to the cargo load.
Rui Chen et al.
PloS one, 12(12), e0190241-e0190241 (2017-12-28)
Survival of cancer cells in the harsh tumor microenvironment, characterized by oxygen and glucose deprivation, requires rapid initiation of cytoprotective measures. Metabolites whose levels change during stress are ideal signaling cues, particularly if used in post-translational modifications of stress-responsive signal
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