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H5667

Sigma-Aldrich

Suero humano

Heat Inactivated (from male AB clotted whole blood), USA origin, sterile-filtered

Sinónimos:

HI Human sera, HI Human serum, HI OTC, Human Serum, human sera, off the clot, otc

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About This Item

Número MDL:
Código UNSPSC:
12352207
NACRES:
NA.71
origen biológico:
human
origen:
USA origin
esterilidad:
sterile-filtered
Condiciones de envío:
dry ice
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

human

Nivel de calidad

esterilidad

sterile-filtered

composición

Hemoglobin, ≤25 mg/dL

origen

USA origin

técnicas

cell culture | mammalian: suitable
cell culture | stem cell: suitable

impurezas

≤10 EU/mL Endotoxin

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

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Aplicación

Human AB serum is used in tissue engineering, transplantation and cell therapy applications for the expansion of mesenchymal stem cells (MSC) from adipose tissue or mesenchymal stromal cells from human bone marrow; for standardized limbal epithelial stem cell graft generation and transplantation; for ex vivo expansion of NK cells from peripheral blood in Hematopoeitic Stem Cell Expansion Medium; and for upgrading pretransplant human islet culture technology.

Envase

Packaging may vary for different batches due to short supply of the bottles used to pack this product. The presence or lack of shrink wrap around the cap of the bottle doesn’t impact product integrity/sterility of the product.

Advertencia

Each donor is tested for and found non-reactive for Hepatitis B & C and non-reactive for Human Immunodeficiency Virus (HIV) antibody by ELISA. Nevertheless, products of human origin should be considered potentially infectious and handled accordingly.

Nota de análisis

Analizada la presencia de endotoxinas

Otras notas

It is not unusual for our human serum products to be cloudy. This product is from pooled serum and cloudiness indicates that lipids are present in the serum. No clear, lipid-free human serum products are available.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Tsvetana Petrova et al.
Scientific reports, 10(1), 3479-3479 (2020-02-28)
Type 2 Innate lymphoid cells (ILC2s) are implicated in helminth infections and asthma where they play a role in the production of Th2-type cytokines. ILC2s express the IL-33 receptor and are a major cell type thought to mediate the effects
Lelia Lavalett et al.
Frontiers in immunology, 11, 630-630 (2020-05-07)
Mycobacterium tuberculosis (Mtb) infects alveolar macrophages (AMs), causing pulmonary tuberculosis (PTB), the most common form of the disease. Less frequently, Mtb is disseminated to many other organs and tissues, resulting in different extrapulmonary forms of TB. Nevertheless, very few studies
Torkild Visnes et al.
Nucleic acids research, 48(21), 12234-12251 (2020-11-20)
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise
Julie Kerr-Conte et al.
Transplantation, 89(9), 1154-1160 (2010-01-26)
BACKGROUND.: The original Edmonton protocol used fresh islets, but for obvious logistic advantages most transplant centers have implemented pretransplant culture in human albumin. The aim of this study was to improve current pretransplant human islet culture techniques. METHODS.: Clinical-grade purified
A Poloni et al.
Cytotherapy, 11(2), 153-162 (2009-03-21)
Mesenchymal stromal cells (MSC) are promising candidates for cell therapy and tissue engineering and may be used to treat acute graft-versus-host disease (GvHD). However, major obstacles for their clinical use are the required cell dose and the biosafety and potential

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Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.

Questions

1–4 of 4 Questions  
  1. What is the percentage of Albumin Human serum in the solution and also provide with the purity of the solution?

    1 answer
    1. This product is Human Serum, not Albumin Human serum. The purity is not measured for the product. The specification of Total Albumin is 4.0 - 9.0 g/dl.

      Helpful?

  2. How many donors are used in each batch?

    1 answer
    1. The average batch of these products is derived from a pool of 180 donors, which may vary from lot to lot.

      Helpful?

  3. What is the difference between human serum from AB plasma and  human serum from AB clotted whole blood?

    1 answer
    1. Product H6914 is prepared from whole blood that is allowed to clot, centrifuged and the serum removed. There is no additional processing required.Product H4522 is prepared from anticoagulated (sodium citrate) whole blood. This is centrifuged to pellet the cells (RBC, WBC, some platelets) and the plasma is removed. This plasma is then treated with calcium to activate the clotting cascade. The preparation is centrifuged again and the supernatant is removed. This product can also be called plasma derived serum.Product H6914 will contain more growth factors since it is allowed to spontaneously clot and there will be the release of growth factors from many of the cells (WBC, platelets) present.  The cells are removed before the plasma is clotted for Product H4522, so this plasma will have fewer growth factors present (more similar to what is circulating). Unless testing for growth factors, most researchers are looking for Product H6914.We offer both products heat inactivated.Product H5667 Human Serum Heat Inactivated, from male AB clotted whole bloodProduct H3667 Human Serum Heat Inactivated, from human male AB plasma

      Helpful?

  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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