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E45309

Sigma-Aldrich

Ethyl phenylpropiolate

98%

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About This Item

Fórmula lineal:
C6H5C≡CCOOC2H5
Número de CAS:
2216-94-6
Peso molecular:
174.20
Beilstein/REAXYS Number:
639637
EC Number:
218-703-8
MDL number:
MFCD00009185
UNSPSC Code:
12352100
PubChem Substance ID:
24894561
NACRES:
NA.22

assay

98%

form

liquid

refractive index

n20/D 1.552 (lit.)

bp

260-270 °C (lit.)

density

1.055 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOC(=O)C#Cc1ccccc1

InChI

1S/C11H10O2/c1-2-13-11(12)9-8-10-6-4-3-5-7-10/h3-7H,2H2,1H3

InChI key

ACJOYTKWHPEIHW-UHFFFAOYSA-N

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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K A Davidson et al.
The Journal of investigative dermatology, 79(6), 378-382 (1982-12-01)
Glucocorticoids (anti-inflammatory steroids) are very potent inhibitors of mouse skin tumor promotion induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). This report describes a high-affinity, limited-capacity binding component which specifically interacts with glucocorticoids and which is identified as a glucocorticoid (GC) receptor present in
J E Paulsen
Carcinogenesis, 11(8), 1255-1258 (1990-08-01)
We examined the effects of retinoic acid (RA) on epidermal DNA synthesis, induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a strong tumor promoter; mezerein (MEZ), a strong second stage promoter or ethylphenylpropiolate (EPP), a weak tumor promoter. RA reduced the initial wave of
G S Cameron et al.
Cancer research, 51(20), 5642-5648 (1991-10-15)
The ability of the hyperplasiogenic irritant ethyl phenylpropiolate (EPP) to act as a tumor promoter in two-stage carcinogenesis and to stimulate cellular events commonly cited as markers of tumor promoter action was evaluated. Treatment of adult, inbred SENCAR (SSIN) mice
P Claeson et al.
Planta medica, 62(3), 236-240 (1996-06-01)
The topical anti-inflammatory activity of three non-phenolic linear 1,7-diarylheptanoids, previously isolated from a Thai medicinal plant, Curcuma xanthorrhiza (Zingiberaceae) and four new semi-synthetic derivatives of the naturally occurring compounds were assessed in the murine model of ethyl phenylpropiolate-induced ear edema.
Ampai Panthong et al.
Journal of ethnopharmacology, 91(2-3), 237-242 (2004-05-04)
Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It
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