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678937

Sigma-Aldrich

Tris[(1-benzyl-1H-1, 2, 3-triazol-4-yl)methyl]amine

97%

Sinónimos:

TBTA

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About This Item

Fórmula empírica (notación de Hill):
C30H30N10
Número de CAS:
510758-28-8
Peso molecular:
530.63
Número MDL:
MFCD09265124
Código UNSPSC:
12161600
ID de la sustancia en PubChem:
24884865
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nivel de calidad

200

Ensayo

97%

Formulario

solid

idoneidad de la reacción

reagent type: ligand
reaction type: click chemistry

mp

132-143 °C

temp. de almacenamiento

−20°C

cadena SMILES

C(N(Cc1cn(Cc2ccccc2)nn1)Cc3cn(Cc4ccccc4)nn3)c5cn(Cc6ccccc6)nn5

InChI

1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2

Clave InChI

WKGZJBVXZWCZQC-UHFFFAOYSA-N

Categorías relacionadas

Aplicación

A polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.[1]

Producto relacionado

Referencia del producto
Descripción
Precios

906301

BTTES

906328

BTTAA, ≥95%

Frases de peligro

H413

Clasificaciones de peligro

Aquatic Chronic 4

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
WXBF4908V
WXBF0600V
WXBD8776V
MKCQ4523
MKCK8109

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Frank Iversen et al.
Theranostics, 3(3), 201-209 (2013-03-09)
Some of the main concerns with in vivo application of naked small interfering RNA are rapid degradation and urinary excretion resulting in a short plasma half-life. In this study we investigated how conjugation of polyethylene glycol (PEG) with variable chain
Timothy R Chan et al.
Organic letters, 6(17), 2853-2855 (2004-08-28)
Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.
Brent R Martin et al.
Nature methods, 9(1), 84-89 (2011-11-08)
The reversible thioester linkage of palmitic acid on cysteines, known as protein S-palmitoylation, facilitates the membrane association and proper subcellular localization of proteins. Here we report the metabolic incorporation of the palmitic acid analog 17-octadecynoic acid (17-ODYA) in combination with
Qian Wang et al.
Journal of the American Chemical Society, 125(11), 3192-3193 (2003-03-13)
The copper-catalyzed cycloaddition reaction between azides and alkynes functions efficiently in aqueous solution in the presence of a tris(triazolyl)amine ligand. The process has been employed to make rapid and reliable covalent connections to micromolar concentrations of protein decorated with either
Xiangyu Zhang et al.
Therapeutic advances in medical oncology, 12, 1758835920947976-1758835920947976 (2020-10-01)
Aspirin has recently emerged as an anticancer drug, but its therapeutic effect on lung cancer has been rarely reported, and the mechanism of action is still unclear. Long-term use of celecoxib in large doses causes serious side effects, and it
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