I3275
Interferon-γ from rat
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonyme(s) :
IFN-γ
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About This Item
Produits recommandés
Source biologique
rat
Niveau de qualité
Produit recombinant
expressed in E. coli
Pureté
≥97% (SDS-PAGE)
Forme
lyophilized powder
Poids mol.
15.5 kDa
Conditionnement
pkg of 0.1 mg
Technique(s)
cell culture | mammalian: suitable
Impuretés
endotoxin, tested
Couleur
white
Numéro d'accès UniProt
Température de stockage
−20°C
Informations sur le gène
rat ... Ifng(25712)
Application
Interferon-γ from rat has been used to study the effect of lipoxin A4 and 17(R)-resolvin D1 on lipopolysaccharide and interferon-γ-mediated tumor necrosis factor release in rat astrocyte culture. In rats, it has been used in the treatment of INS-1 cell culture to study the conversion factors which change the frequency of β-cell replication or apoptosis to rates of replication or apoptosis.
Actions biochimiques/physiologiques
Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. In rats, it is upregulated during ischemic injury in the embolic stroke. In cultured rat intestinal mucosa microvascular endothelial cells, ifng is responsible for inducing expression of interferon-α and interferon-β.
Caractéristiques et avantages
The biological activity is measured in an anti-viral assay using L-929 cells infected with EMC virus.
Forme physique
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 50 μg of bovine serum albumin per 1 μg of cytokine.
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
Certificats d'analyse (COA)
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Les clients ont également consulté
Meager, A. et al.
Lymphokines and Interferons, A Practical Approach, 129-129 (1987)
Sally Abdelmoaty et al.
PloS one, 8(9), e75543-e75543 (2013-10-03)
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if
Zhen-Jie Wang et al.
iScience, 24(11), 103280-103280 (2021-11-13)
Nitric oxide (NO) is an important immune molecule that acts against extracellular and intracellular pathogens in most hosts. However, after the knockout of inducible nitric oxide synthase (iNOS -/-) in Sprague Dawley (SD) rats, these iNOS -/- rats were found
Hamid Reza Jafarinaveh et al.
Iranian journal of allergy, asthma, and immunology, 13(2), 125-130 (2013-12-18)
Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because
R Dijkema et al.
The EMBO journal, 4(3), 761-767 (1985-03-01)
The chromosomal immune interferon gene of the rat (IFN-gamma) was identified by screening a recombinant rat lambda phage library with a human IFN-gamma cDNA probe. In contrast to the genes of other rat IFNs, this rat IFN-gamma chromosomal gene contains
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