T0632

Sodium thioglycolate

≥96.5% (iodometric)

• Sinónimos: Mercaptoacetic acid sodium salt, Thioglycolic acid sodium salt
• Fórmula lineal: HSCH₂COONa
• Número de CAS: 367-51-1
• Peso molecular: 114.10
• Beilstein: 4569109
• Número CE: 206-696-4
• Número MDL: MFCD00043386
• Código UNSPSC: 12352201
• ID de la sustancia en PubChem: 24899901
• NACRES: NA.25

Propiedades

• Ensayo: ≥96.5% (iodometric)
• Formulario: powder
• color: white to off-white
• intervalo de pH útil: 6.7 (20 °C, 100 g/L)
• mp: >300 °C (lit.)
• solubilidad: water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].[O-]C(=O)CS
• InChI: 1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
• Clave InChI: GNBVPFITFYNRCN-UHFFFAOYSA-M

Descripción

Aplicación

Sodium thioglycolate has been used:

• as a growth supplement in enrichment media and to study its effect on Arcobacter
• in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
• in electron microscopy

Acciones bioquímicas o fisiológicas

Sodium thioglycolate acts as reducing agent and is suitable for anaerobic and microaerophilic bacterial growth.

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Precaución

At room temperature, concentrations over 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acidic or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• Pictogramas: GHS06,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H290,H301,H312,H317,H412
• Consejos de prudencia: P234 - P261 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Clasificaciones de peligro: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves