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Merck

N1377

Sigma-Aldrich

4-Nitrophenyl α-D-glucopyranoside

chromogenic, ≥99%, powder or crystals

Sinónimos:

p-Nitrophenyl α-D-glucopyranoside

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1 G
$104.000
5 G
$205.000
25 G
$912.000

$104.000


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1 G
$104.000
5 G
$205.000
25 G
$912.000

About This Item

Fórmula empírica (notación de Hill):
C12H15NO8
Número de CAS:
Peso molecular:
301.25
Beilstein:
92212
Número CE:
Número MDL:
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
NACRES:
NA.32

$104.000


En stockDetalles


Nombre del producto

4-Nitrophenyl α-D-glucopyranoside, ≥99%

Nivel de calidad

Ensayo

≥99%

Formulario

powder or crystals

solubilidad

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

temp. de almacenamiento

−20°C

cadena SMILES

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

Clave InChI

IFBHRQDFSNCLOZ-ZIQFBCGOSA-N

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Aplicación

4-Nitrophenyl ǥ-D-glucopyranoside has been used as a substrate in an ǥ-glucosidase inhibition assay.[1][2][3]

Acciones bioquímicas o fisiológicas

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.[4]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosidase inhibitors, and antioxidant compounds are known to manage diabetes and have received much attention recently.
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Candida albicans is a major invasive pathogen, and the development of strains resistant to conventional antifungal agents has been reported in recent years. We evaluated the antifungal activity of 44 compounds against Candida strains. Magnoflorine showed the highest growth inhibitory
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Herein, substituted imidazole-pyrazole hybrids (2a-2n) were prepared via a multi component reaction employing pyrazole-4-carbaldehydes (1a-1d), ammonium acetate, benzil and arylamines as reactants. All the new compounds were characterized through their spectral and elemental analyses. Further these compounds were tested against

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Questions

1–4 of 4 Questions  
  1. How is 4-Nitrophenyl α-D-glucopyranoside, Product N1377, used?

    1 answer
    1. 4-Nitrophenyl α-D-glucopyranoside is used as a substrate for the assay of α-glucosidase.  A stock solution of 4 mM is prepared in deionized water.  Upon the enzymatic hydrolysis of this substrate, 4-nitrophenol is produced.  The molar extinction coefficient of 4-nitrophenol in 0.01 M NaOH (pH 10.2) is approximately 18,380 at 400 nm.

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  2. What is the melting point and specific rotation for 4-Nitrophenyl α-D-glucopyranoside, Product N1377?

    1 answer
    1. The melting point range from our MSDS is 209-213 °C.  The optical rotation is lot specific, and can be found on the Certificate of Analysis at our website.

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  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. What is the solubility of 4-Nitrophenyl α-D-glucopyranoside, Product N1377?

    1 answer
    1. We test the solubility of 4-Nitrophenyl α-D-glucopyranoside at 20 mg/mL in methanol.  When 4-Nitrophenyl α-D-glucopyranoside is used as a substrate for α-glucosidase, a 4 mM stock solution is made in water.

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