C7821
Curdlan
from Alcaligenes faecalis, ≥98% (TLC), solid
Sinónimos:
β-1,3-Glucan hydrate
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Productos recomendados
General description
Curdlan is an insoluble natural polymer with linear structure mainly produced by Alcaligenes faecalis. It is a dietary fiber with gelatin properties.
Application
Curdlan from Alcaligenes faecalis has been used:
- for the stimulation of carp macrophages for regulation of differentially expressed genes
- to stimulate human intestinal epithelial cells for cytokine secretion
- to study its effect on transcriptional responses of inflammation/respiratory burst-associated genes in mouse alveolar macrophages by customized reverse transcription (RT)-PCR based arrays
- as a substrate in β-1,3–1,4-Glucanase activity assay
Biochem/physiol Actions
Curdlan is used as a food additive in the food industry. It improves the elasticity and reduces the embrittling tendency of hydroxyapatite/chitosan scaffold, which aids in bone regeneration.
Curdlan is a (1,3)-β-glucan. It is a pathogen-associated molecular-pattern (PAMP) recognized by the receptor dectin-1. Activation of dectin-1, together with TLR2/TLR6, promotes signaling resulting in the production of pro-inflammatory cytokines, thus inducing inflammation.
Preparation Note
For gelation at 70 °C, the concentration of the sodium hydroxide should be 0.01 M.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Los clientes también vieron
Nicola Jackson et al.
European journal of immunology, 44(4), 962-969 (2014-01-25)
Type B T cells recognize peptide-MHC class II (pMHCII) isoforms that are structurally distinct from those recognized by conventional type A T cells. These alternative type B conformers result from peptide loading in the absence of HLA-DM. Type A conformers
Microbial exopolisaccharides for biomedical applications
Journal of Material Science & Engineering, 165-219 (2019)
Chunju An et al.
The Journal of biological chemistry, 284(29), 19716-19726 (2009-06-03)
Serine proteinases in insect plasma have been implicated in two types of immune responses; that is, activation of prophenoloxidase (proPO) and activation of cytokine-like proteins. We have identified more than 20 serine proteinases in hemolymph of the tobacco hornworm, Manduca
Characterisation of a novel Bacillus sp. SJ-10 I?-1,3-1,4-glucanase isolated from jeotgal, a traditional Korean fermented fish.
Kim, et al.
Bioprocess and Biosystems Engineering, 36, 721-727 (2013)
Jing Li et al.
Applied microbiology and biotechnology, 97(19), 8495-8503 (2013-07-31)
Biologically active β-1,3-oligosaccharides with rapidly growing biomedical applications are produced from hydrolysis of curdlan polysaccharide. The water-insoluble curdlan impedes its hydrolysis efficiency which is enhanced by our newly developed alkali-neutralization treatment process to increase the stability of curdlan suspension to
Artículos
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico