C6895

Cefaclor

• Sinónimos: 7-(D-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid
• Fórmula empírica (notación de Hill): C₁₅H₁₄ClN₃O₄S
• Número de CAS: 53994-73-3
• Peso molecular: 367.81
• Beilstein: 8176092
• Número CE: 258-909-5
• Número MDL: MFCD00151471
• Código UNSPSC: 51283701
• ID de la sustancia en PubChem: 24278331
• NACRES: NA.85

Propiedades

• Formulario: powder or crystals
• Nivel de calidad: 200
• solubilidad: soluble (slightly soluble in water, practically insoluble in methanol, ethanol)
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria
• Modo de acción: cell wall synthesis | interferes
• cadena SMILES: N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c3ccccc3
• InChI: 1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1
• Clave InChI: QYIYFLOTGYLRGG-GPCCPHFNSA-N

Descripción

Descripción general

Chemical structure: ß-lactam

Aplicación

Cefaclor has been used in the heterologous expression of AaOr7 and AaOr8 in Xenopus laevis oocytes. It has also been used in cultures of isolated trigeminal ganglion (TG) and dorsal root ganglion (DRG) neurons.

Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections . It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis .

Acciones bioquímicas o fisiológicas

Cefaclor is a second generation cephalosporin with broad spectrum activity against Gram-negative and Gram-positive bacteria. It binds to penicillin-binding proteins and thereby inhibits the cell wall synthesis causing cell death.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Slightly soluble in water, practically insoluble in methanol, chloroform and benzene.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves