Pharmacology, biochemistry, and behavior, 75(3), 619-625 (2003-08-05)
Because extracts of kudzu have been used as a hangover remedy in China for many centuries, we tested the ability of NPI-031G (puerarin), an isoflavone isolated from kudzu, to counteract anxiogenic effects associated with withdrawal from chronic alcohol exposure. NPI-O31G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 52, 69-75 (2012-11-14)
This study was designed to evaluate the potential effects of puerarin (PR), an effective isoflavonoid compound purified from Pueraria lobata, in treating hepatic fibrosis (HF) rats induced by carbon tetrachloride (CCl(4), 2 mL kg(-1) d(-1)). Compared to model control, PR
Journal of agricultural and food chemistry, 60(51), 12501-12507 (2012-12-12)
Puerarin is a natural isoflavone, found in the Chinese medicinal plant Ge-gen, with many reported health-promoting properties. However, its low water solubility impedes its application in pharmaceutical and functional food products. This study explores the formation of inclusion complex between
Human & experimental toxicology, 32(2), 172-185 (2013-01-15)
Puerarin (PU), a natural flavonoid, has been reported to possess anti-oxidative and anti-inflammatory activities. In the present study, female Sprague-Dawley rats received lead (Pb) nitrate (300 mg/L, via drinking water) and/or PU (400 mg/kg/day, orally) to investigate the protective effects of PU
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(1), 49-52 (2013-04-20)
To prepare membrane controlled tablets of puerarin sinclusion compound and to investigate the drug release in vitro. The single factors affecting drug release in vitro were investigated. Then, uniform design was used to optimize the formulation of controlled osmotic-pump tablets.
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