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Merck

PHR1196

Supelco

Nitrofurazone

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

5-Nitro-2-furaldehyde semicarbazone, NZ, Nitrofural, 5-Nitro-2-furfural semicarbazone, Furacin, NFZ, Nitrofurazone

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About This Item

Fórmula empírica (notación de Hill):
C6H6N4O4
Número de CAS:
Peso molecular:
198.14
Beilstein:
86403
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to Ph. Eur. N0950000
traceable to USP 1465004

familia API

nitrofurazone

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

242-244 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

Clave InChI

IAIWVQXQOWNYOU-FPYGCLRLSA-N

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Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

Nitrofurazone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by DC polarography, chromatography and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC0296 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogramas

Health hazardExclamation mark

Palabra de señalización

Warning

Clasificaciones de peligro

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2

Órganos de actuación

male reproductive organs

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3


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Certificados de análisis (COA)

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Inclusion compounds in pharmaceutical analysis II: Assay of a cream following chemical dehydration
Hays SE and Grady LT
Journal of Pharmaceutical Sciences, 60(2), 295-298 (1971)
Electrochemical reduction of nitrofurazone and its determination in pharmaceutical dosage forms by Dc polarography
Mishra AK and Gode KD
Analyst, 110(11), 1373-1376 (1985)
Teresa del Castillo et al.
ChemMedChem, 9(2), 383-389 (2013-12-18)
Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad hoc synthesis of each cyclodextrin-targeting agent conjugate. We
Robert Pickard et al.
Lancet (London, England), 380(9857), 1927-1935 (2012-11-09)
Catheter-associated urinary tract infection (CAUTI) is a major preventable cause of harm for patients in hospital. We aimed to establish whether short-term routine use of antimicrobial catheters reduced risk of CAUTI compared with standard polytetrafluoroethylene (PTFE) catheterisation. In our parallel
James R Johnson et al.
The Journal of urology, 184(6), 2572-2577 (2010-10-30)
We determined the activity, comparative potency and effect durability of commercially available, antimicrobial coated Foley catheters against Escherichia coli isolates, including extended spectrum cephalosporin resistant strains. We used an inhibition zone assay (diffusible inhibition) and an adherence assay (diffusible and

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