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Documentos clave

M1755000

Methylprednisolone acetate

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate

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About This Item

Fórmula empírica (notación de Hill):
C24H32O6
Número de CAS:
Peso molecular:
416.51
Número CE:
Código UNSPSC:
41116107
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

methylprednisolone

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@@]4(C(=CC(=O)C=C4)[C@H](C3)C)C)[C@H](C2)O)CC1)C)C(=O)COC(=O)C

InChI

1S/C24H32O6/c1-13-9-16-17-6-8-24(29,20(28)12-30-14(2)25)23(17,4)11-19(27)21(16)22(3)7-5-15(26)10-18(13)22/h5,7,10,13,16-17,19,21,27,29H,6,8-9,11-12H2,1-4H3/t13-,16-,17-,19-,21+,22-,23-,24-/m0/s1

Clave InChI

PLBHSZGDDKCEHR-LFYFAGGJSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Methylprednisolone acetate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Health hazard

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Repr. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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John P Caron et al.
Veterinary surgery : VS, 42(3), 231-237 (2013-01-03)
To compare the effects of triamcinolone acetonide (TA) and methylprednisolone acetate (MPA) on expression of selected chondrocyte genes in recombinant equine interleukin-1β (reIL-1β) stimulated articular cartilage explants. In vitro experiment. Horses (n = 6). Articular cartilage explants from 2- to
Maria Simitsopoulou et al.
Medical mycology, 53(2), 189-193 (2014-07-25)
Exserohilum rostratum caused a multistate fungal meningitis outbreak following iatrogenic inoculation of contaminated methylprednisolone in the United States. To gain insight into the immunopathogenesis of this infection, we studied the innate host responses of human neutrophils against E. rostratum conidia
Felix P Aplin et al.
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To develop and characterize a feline model of retinal degeneration induced by intravitreal injection of adenosine triphosphate (ATP). Nineteen normally sighted adult cats received 100 μL intravitreal injections of ATP with a final concentration of 11, 22, or 55 mM
Jennifer L Lyons et al.
Journal of clinical microbiology, 51(4), 1285-1287 (2013-02-01)
This case series highlights our experience with use of the Fungitell assay for quantifying (1,3)-β-d-glucan in cerebrospinal fluid during the current U.S. outbreak of fungal meningitis related to contaminated methylprednisolone acetate. This test may prove a useful adjunct in diagnosis
Kirk Kleinfeld et al.
JAMA neurology, 70(9), 1173-1176 (2013-07-24)
Fungal meningitis due to injections of contaminated methylprednisolone acetate can present with vascular sequelae in immunocompetent individuals. This is particularly germane to neurologists because better recognition of the clinical characteristics of patients with fungal meningitis and ischemic stroke will provide

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