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Merck

31550

Supelco

2,3-Butanedione monoxime

for spectrophotometric det. of urea, ≥99.0%

Sinónimos:

BDM

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About This Item

Fórmula lineal:
CH3C(=NOH)COCH3
Número de CAS:
Peso molecular:
101.10
Beilstein:
605582
Número CE:
Número MDL:
Código UNSPSC:
41116105
ID de la sustancia en PubChem:
NACRES:
NA.21

Nivel de calidad

Ensayo

≥98.0% (N)
≥99.0%

Formulario

solid

calidad

for spectrophotometric det. of urea

técnicas

UV/Vis spectroscopy: suitable

residuo de ign.

≤0.05% (as SO4)

bp

185-186 °C (lit.)

mp

75-76 °C
75-78 °C (lit.)

cadena SMILES

CC(=O)\C(C)=N\O

InChI

1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+

Clave InChI

FSEUPUDHEBLWJY-HWKANZROSA-N

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Descripción general

2,3-Butanedione Monoxime (BDM) is also known as diacetyl monoxime, it is also a nucleophilic agent and it can dephosphorylates acetylcholinesterase poisoned with organophosphates. It is also a well-characterized, non-competitive inhibitor of skeletal muscle myosin-II, where it inhibits the chemical and motile activity.

Aplicación


  • A novel method to extend viability and functionality of living heart slices.: This research introduces a novel application of 2,3-Butanedione monoxime for prolonging the functional lifespan of cardiac tissue samples in experimental settings, offering insights into cardiac biology and potential therapeutic targets (Ross et al., 2023).

  • Molecular Mechanisms of Deregulation of Muscle Contractility Caused by the R168H Mutation in TPM3 and Its Attenuation by Therapeutic Agents.: The study utilizes 2,3-Butanedione monoxime to investigate the molecular pathways affected by genetic mutations in muscle contractility, contributing to the understanding of muscle disorders and their management (Karpicheva et al., 2023).

  • Generation of myocyte agonal Ca(2+) waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation.: Research employing 2,3-Butanedione monoxime investigates its role in inducing specific cellular events in cardiac cells under stress, highlighting its potential in studies of heart disease mechanisms and therapies (Morishita et al., 2023).


Nota de análisis

Solubility:
0.5 g are completely soluble and give a clear solution in 10 mL water or also in 10 mL ethanol.
Sensitivity test:
0.05 mg urea in 3 mL water and 5 mL conc. HCl together with a 3% solution in water of diacetylmonoxime heated on a water bath for 10 minutes give a light yellow color.

Otras notas

Reagent for the colorimetric determination of urea and ureido-compounds; Spectrometric reagent for Co(II), Ni(II), Pd(II) and Re(VII); Reagent for the gravimetric determination of Ni(II)

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Visite la Librería de documentos

W.B. Guenther
Analytical Letters, 12A, 1305-1305 (1979)
Improvements on the Prescott-Jones method for the colorimetric analysis of ureido compounds.
D B Shindler et al.
Analytical biochemistry, 97(2), 421-422 (1979-09-01)
2, 3-Butanedione monoxime (BDM) as a myosin inhibitor.
Ostap EM.
Journal of Muscle Research and Cell Motility, 23 (4), 305-308 (2002)
Multiple Effects of 2, 3-Butanedione Monoxime.
Sellin LC and McArdle JJ/
Pharmacology & Toxicology, 74 (4-5), 305-313 (1994)
Chang Liu et al.
Molecular plant, 11(11), 1389-1399 (2018-10-09)
The process of pollen germination is crucial for flowering plant reproduction, but the mechanisms through which pollen grains establish polarity and select germination sites are not well understood. In this study, we report that a formin family protein, AtFH5, is localized

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