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AB9983

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

rabbit polyclonal

Sinónimos:

Tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Nombre del producto

Anti-Tyrosine Hydroxylase Antibody, from rabbit

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

rat, mouse

técnicas

immunohistochemistry: suitable (paraffin)
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

mouse ... Th(21823)
rat ... Th(25085)

Descripción general

Tyrosine Hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines Dopamine and Norepinephrine from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. The enzymatic activity of TH requires ferrous ions as cofactors and is believed to be regulated by phosphorylation. At least four isoforms of human TH have been identified which result from alternative splicing.

Especificidad

Cat. # AB9983 recognizes the C-terminus of Tyrosine Hydroxylase
Reactivity with other species has not been determined.

Inmunógeno

Epitope: C-terminus
Recombinant protein

Aplicación

Anti-Tyrosine Hydroxylase Antibody detects level of Tyrosine Hydroxylase & has been published & validated for use in IH(P) & WB.
Immunohistochemistry: 1:100 working dilutions were used on rat and mouse brain (paraffin embedded tissue).
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Descripción de destino

~ 58 kDa

Forma física

Antigen Affinity Purified
Format: Purified
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3

Almacenamiento y estabilidad

Stable for 1 year at 2-8ºC from date of receipt.

Nota de análisis

Control
Rat Brain lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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