1.16855

Superspher^® 100 RP-18 endcapped (4µm) HPLC Columns

L x I.D. 125 mm x 4 mm, LiChroCART^™ HPLC cartridge, manuCART^™ holder required for use

• Sinónimos: TM=["Superspher"] C18 TM=["LICHROCART"] cartridge for HPLC
• Código UNSPSC: 41115709
• NACRES: SB.52

Propiedades

• Nombre del producto: Superspher^® 100 RP-18 endcapped LiChroCART^™ 125-4, suitable for HPLC
• Materiales: stainless steel column
• Nivel de calidad: 100
• Agency: suitable for USP L1
• Línea del producto: Superspher^®
• Características: endcapped
• Parámetros: 250 bar pressure; 60 °C max. temp.
• técnicas: HPLC: suitable; mass spectrometry (MS): suitable (Low - Medium)
• columna L × D.I.: 12.5 cm × 4 mm
• Matriz: fully porous particle
• grupo activo de la matriz: C18 bonding phase
• tamaño de partícula: 4 μm
• tamaño de poro: 100 Å pore size
• Intervalo de pH operativo: 2-7.5
• técnica de separación: reversed phase
• temp. de almacenamiento: no temp limit

Descripción

Descripción general

HPLC cartridge

Superspher^® RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carriers with C-18 endcapped reversed phase properties. They are well suited for the separation of neutral, acidic and weak basic compounds. This high performance silica carrier with a particle size of 4µm yields an excellent pressure/separation performance ratio.This sorbent is packed into a LiChroCART 125-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).

Aplicación

• Chemometric approach for estimation of ropinirole hydrochloride: This study presents a chemometric approach for the development and validation of an HPLC method for estimating ropinirole hydrochloride using LiChrospher 100 RP-18 columns. The method shows robustness and efficiency for pharmaceutical analysis (Fatima et al., 2019).


• Simultaneous quantification of Parkinson′s disease medications: An HPLC method using LiChrospher 100 RP-18 was validated for simultaneous quantification of levodopa, carbidopa, benserazide, and entacapone in complex matrices, proving its capability in pharmaceutical formulations (Wollmer & Klein, 2017).


• Stability of THCA and (9)-THC in herbal cannabis: This research employed LiChrospher 100 RP-18 columns to determine the stability of THCA and Δ(9)-THC in herbal cannabis under different storage temperatures, important for forensic and pharmaceutical sciences (Taschwer & Schmid, 2015).


• Stability indicating method for cilazapril: Researchers developed a rapid and simple stability-indicating HPLC method for cilazapril, using LiChrospher 100 RP-18, to assess drug stability in pharmaceuticals, compared to spectrophotometric methods, highlighting its precision and reliability (Paszun et al., 2012).

Nota de análisis

Pressure: ≤ 80 bar
Theoretical Plates (N/m) (Anthracene): ≥ 100000
Symmetry (Anthracene): 0.8 - 1.4
Capacity factor (Anthracene): 3.5 - 5.5

Información legal

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany

Superspher is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids