1.11452

Phthaldialdehyde

for fluorometry

• Sinónimos: Phthaldialdehyde, OPA
• Fórmula lineal: C₆H₄-1,2-(CHO)₂
• Número de CAS: 643-79-8
• Peso molecular: 134.13
• MDL number: MFCD00003335
• UNSPSC Code: 12352114
• EC Index Number: 211-402-2
• NACRES: NA.21

Propiedades

• Quality Level: 100
• form: solid
• autoignition temp.: 480 °C
• potency: 178 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 7 (20 °C, 53 g/L in H₂O)
• bp: 83-84 °C/1 hPa
• mp: 52-58 °C
• transition temp: flash point 132 °C
• solubility: 53 g/L
• density: 1.13 g/cm³ at 20 °C
• bulk density: 530 kg/m³
• storage temp.: 2-30°C
• InChI: 1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
• InChI key: ZWLUXSQADUDCSB-UHFFFAOYSA-N

Descripción

Application

• Combined techniques for revealing the mechanism beneath the inhibition effects of pectin on gluten digestibility using static in vitro gastro-duodenal protocols.: This study uses a combination of techniques to explore how pectin affects gluten digestibility, providing insights into the interaction of phthaldialdehyde derivatives with gluten proteins (Lin et al., 2024).


• Analysis of Gizzerosine in Foodstuffs by HPLC Involving Pre-column Derivatization with o-Phthaldialdehyde.: This research develops a method using HPLC with pre-column derivatization involving phthaldialdehyde to analyze gizzerosine in foodstuffs, demonstrating the compound′s utility in food safety studies (Li and Wu, 2024).


• Comprehensive studies on the development of HPLC-MS/MS and HPLC-FL based methods for routine determination of homocysteine thiolactone in human urine.: This study develops and validates methods using phthaldialdehyde derivatives for the determination of homocysteine thiolactone in human urine, contributing to clinical diagnostics and biochemical research (Piechocka and Głowacki, 2024).


• Smart-detection approach for protein residues to evaluate the cleaning efficacy of reusable medical devices.: Utilizing phthaldialdehyde for protein residue detection, this study provides a smart detection approach to improve the cleaning efficacy of medical devices, enhancing patient safety (Ouirungroj et al., 2024).


• One-pot sample preparation procedure for the determination of protein N-linked homocysteine by HPLC-FLD based method.: This research presents a novel one-pot sample preparation method using phthaldialdehyde for determining protein N-linked homocysteine, advancing analytical techniques in protein chemistry (Piechocka and Głowacki, 2023).

Analysis Note

Purity (GC): ≥ 99 %
Identity (IR): conforms
Melting point: 54 - 58 °C
Fluorescence (340 nm, 0,8 g/l, ethanol, as quinine): ≤ 2 ppb
Phthalic acid (TLC): ≤ 0.5 %
Nitrogen compounds (as N): ≤ 0.05 %

Información de seguridad

• pictograms: GHS05,GHS06,GHS09
• signalword: Danger
• hcodes: H301 - H314 - H317 - H335 - H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 269.6 °F - closed cup
• flash_point_c: 132 °C - closed cup