1.03583

Sorbitol Parteck^®

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF, JSFA, E 420

• Sinónimos: Parteck^® Sorbitol, D-Glucitol
• Fórmula empírica (notación de Hill): C₆H₁₄O₆
• Número de CAS: 50-70-4
• Peso molecular: 182.17
• Número MDL: MFCD00004708
• Código UNSPSC: 12352201
• Número E: E420

Propiedades

• Agency: BP; JP; JSFA; NF; Ph. Eur.
• Nivel de calidad: 500
• Línea del producto: EMPROVE^® ESSENTIAL
• Formulario: fine powder
• temp. de autoignición: 420 °C
• tamaño de partícula: (see specification)
• pH: 6-7 (20 °C, 100 g/L in H₂O)
• mp: 94-96 °C
• temperatura de transición: flash point >100 °C
• solubilidad: 2350 g/L
• densidad: 1.49 g/cm³ at 20 °C
• aplicaciones: liquid formulation; pharmaceutical; solid formulation
• temp. de almacenamiento: 2-25°C
• cadena SMILES: OC(C(O)C(O)CO)C(O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2
• Clave InChI: FBPFZTCFMRRESA-UHFFFAOYSA-N

Descripción

Descripción general

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicación

Parteck^® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations. Parteck^® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications.

Características y beneficios

• Excellent direct compression properties
• High dilution and adsorption capacity
• Larger and highly structured surface area
• Low hygroscopicity
• Low amount of reducing sugars

Almacenamiento y estabilidad

Storage temperature: no restrictions.

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable