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791649C

Avanti

18:1-d9 SM

Avanti Research - A Croda Brand

Sinónimos:

N-oleoyl(d9)-D-erythro-sphingosylphosphorylcholine

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1 MG
$282.000

$282.000


Fecha estimada de envío25 de abril de 2025


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1 MG
$282.000

About This Item

Fórmula empírica (notación de Hill):
C41H72 D9N2O6P
Número de CAS:
Peso molecular:
738.12
Número MDL:
Código UNSPSC:
41141825
NACRES:
NA.25

$282.000


Fecha estimada de envío25 de abril de 2025


Solicitar un pedido a granel

Ensayo

>99% (TLC)

Formulario

liquid

envase

pkg of 1 × 1 mL (791649C-1mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand

concentración

1 mg/mL (791649C-1mg)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

18:1-d9 SM (N-oleoyl(d9)-D-erythro-sphingosylphosphorylcholine) is a deuterated derivative of 18:1-SM (N-oleoyl-D-erythro-sphingosylphosphorylcholine). 18:1- SM is a sphingomyelin which is present in aqueous humor.[1] 18:1-SM or oleoyl-sphingomyelin, comprises quaternary ammonium group.[2] 18:1-SM or oleoyl-sphingomyelin due to its miscible property is incapable of sequestering with cholesterol-rich domains.[2]
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH LIPIDOMIX Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Aplicación

18:1-d9 SM (N-oleoyl(d9)-D-erythro-sphingosylphosphorylcholine) has been used as an extraction buffer component for lipid isolation from raft and non-raft fractions of synaptic vesicles (SV) from rat brain.[3] It may be used as an internal standard to spike serum lipid extracts for liquid chromatography-mass spectrometry (LC/MS) analysis[4] and ultra-high-performance supercritical fluid chromatography with quadrupole-time-of-flight mass spectrometry (UHPSFC/QTOF-MS) for signal normalization and quantification of pulmonary artery lipids form porcine.[5]

Envase

5 mL Clear Glass Sealed Ampule (791649C-1mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system, Liver,Kidney

Código de clase de almacenamiento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

does not flash

Punto de inflamabilidad (°C)

does not flash


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Richard M Epand et al.
Chemistry and physics of lipids, 132(1), 37-46 (2004-11-09)
Sphingomyelin from biological membranes forms segregated domains with cholesterol in fluid bilayers. However, a synthetic form of sphingomyelin with an oleoyl chain linked to sphingosine is not incorporated into cholesterol-rich domains. We have studied the properties of mixtures of oleoyl-sphingomyelin
Ayman J Aljohani et al.
Molecular vision, 19, 1966-1984 (2013-09-27)
To determine the differential profiles of sphingomyelin, sphingoid base, sphingoid base-1-phosphate and ceramide lipid species and their quantitative differences between control and glaucomatous aqueous humor (AQH) derived from human donors. AQH from control and primary open-angle glaucoma donors was collected
Alicia Gil-Ramirez et al.
Journal of chromatography. A, 1592, 173-182 (2019-02-03)
Pulmonary artery grafts are needed as cardiovascular bioprosthetics. For successful tissue recellularization after transplantation, lipids have to be removed from the donor artery. Developing a selective process to remove lipids without damaging the extracellular matrix greatly depends on knowing the
John Williams et al.
Bioanalysis, 12(3), 143-158 (2020-02-14)
Aim: Very long chain fatty acids (VLCFAs) have been identified as biomarkers for several peroxisomal disorders necessitating the need for reliable biomarker assays in particular C20, C22, C24, C26 in cerebrospinal fluid (CSF). Until now no absolute quantitation assay for
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid

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