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Merck

149357

Sigma-Aldrich

2,5-Dihydroxybenzoic acid

98%

Sinónimos:

2,5-DHBA, DHB, Gentisic acid, Hydroquinonecarboxylic acid

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10 G
$28.300
25 G
$48.800
100 G
$154.000

$28.300


Fecha estimada de envío15 de abril de 2025


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10 G
$28.300
25 G
$48.800
100 G
$154.000

About This Item

Fórmula lineal:
(HO)2C6H3CO2H
Número de CAS:
Peso molecular:
154.12
Beilstein:
2209119
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22

$28.300


Fecha estimada de envío15 de abril de 2025


Solicitar un pedido a granel

Nivel de calidad

Ensayo

98%

Formulario

powder

mp

204-208 °C (lit.)

grupo funcional

carboxylic acid

cadena SMILES

OC(=O)c1cc(O)ccc1O

InChI

1S/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11)

Clave InChI

WXTMDXOMEHJXQO-UHFFFAOYSA-N

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Descripción general

Aspirin metabolite.

Aplicación

2,5-Dihydroxybenzoic acid (2,5-DHBA) can be used:
  • As a matrix in the MALDI-TOF mass spectrometry analysis of the poly(styrene-co-pentafluorostyrene) copolymers.[1]
  • To prepare pharmacologically important 2,5-DBHA-gelatin conjugate, which can act as a polymer for the development of drug formulations.[2]
  • As a tridentate ligand to synthesize complexes of molybdenum by reacting with (PPh4)4Mo8O26.[3]
  • As a starting material in the total synthesis of landomycin A, an angucycline antibiotic.[4]

Pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves


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Certificados de análisis (COA)

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Matrix-assisted laser desorption/ionization sample preparation optimization for structural characterization of poly (styrene-co-pentafluorostyrene) copolymers
Tisdale E, et al.
Analytica Chimica Acta, 808, 151-162 (2014)
Matthew T Briggs et al.
Rapid communications in mass spectrometry : RCM, 31(10), 825-841 (2017-03-09)
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) of the proteome of a tissue has been an established technique for the past decade. In the last few years, MALDI-MSI of the N-glycome has emerged as a novel MALDI-MSI technique. To assess
A 2, 5-Dihydroxybenzoic acid-gelatin conjugate: the synthesis, antiviral activity and mechanism of antiviral action against two alphaherpesviruses
Lisov A, et al.
Viruses, 7(10), 5343-5360 (2015)
Polynuclear oxomolybdenum (VI) complexes of dihydroxybenzoic acids: Synthesis, spectroscopic and structure characterization of a tetranuclear catecholato-type coordinated 2, 3-dihydroxybenzoate and a novel tridentate salicylato-type coordinated 2, 5-dihydroxybenzoate trinuclear complex
Litos C, et al.
Polyhedron, 25(6), 1337-1347 (2006)
Evgenia Tisdale et al.
Analytica chimica acta, 808, 151-162 (2013-12-29)
The influence of the sample preparation parameters (the choice of the matrix, matrix:analyte ratio, salt:analyte ratio) was investigated and optimal conditions were established for the MALDI time-of-flight mass spectrometry analysis of the poly(styrene-co-pentafluorostyrene) copolymers. These were synthesized by atom transfer

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How to prepare a stock solution of 2,5-dihydroxybenzoic acid 149357?

    1 answer
    1. The solubility of this product has not been tested. However, product 85707, which is tested for suitability in Maldi-MS, is tested for solubility at 0.1 g in 10 mL Methanol. These items have the same CAS number and the properties are identical.

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