Passa al contenuto

Unsaturated free fatty acids: a potential biomarker panel for early detection of gastric cancer.

Unsaturated free fatty acids: a potential biomarker panel for early detection of gastric cancer.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2014-10-31)

Yaping Zhang, Ling Qiu, Yanmin Wang, Chengyan He, Xuzhen Qin, Yujie Liu, Zhili Li

ABSTRACT

Changes in the levels of free fatty acids (FFAs) are closely associated with physiological status. Serum levels of C16:1, C18:3, C18:2, C18:1, C20:4, and C22:6 in 164 gastric cancer (GC) patients and 111 benign gastric disease (BGD) patients were significantly decreased compared with 252 healthy controls. Receiver operating characteristic analysis showed that the biomarker panel including C16:1, C18:3, C18:2, C20:4, and C22:6 presents a high diagnostic ability to differentiate early-stage GC patients from healthy controls plus BGD patients, with a sensitivity of 80.6% and a specificity of 72.7%.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

Sigma-Aldrich

Acetonitrile, suitable for HPLC, gradient grade, ≥99.9%

Sigma-Aldrich

Metanolo, suitable for HPLC, ≥99.9%

Sigma-Aldrich

Ethyl alcohol, Pure 200 proof, for molecular biology

Sigma-Aldrich

Metanolo, ACS reagent, ≥99.8%

Sigma-Aldrich

Ethyl alcohol, Pure, 200 proof, ACS reagent, ≥99.5%

Sigma-Aldrich

Acetonitrile, HPLC Plus, ≥99.9%

Sigma-Aldrich

Metanolo, suitable for HPLC, gradient grade, ≥99.9%

Sigma-Aldrich

Metanolo, HPLC Plus, ≥99.9%

Sigma-Aldrich

Ethyl alcohol, Pure, 200 proof, meets USP testing specifications

Sigma-Aldrich

Ammonio acetato, ACS reagent, ≥97%

Sigma-Aldrich

Acetonitrile, ACS reagent, ≥99.5%

Sigma-Aldrich

Acetonitrile, ≥99.9% (GC)

Sigma-Aldrich

Ammonio acetato, ≥99.99% trace metals basis

Sigma-Aldrich

Acetonitrile, suitable for HPLC, gradient grade, ≥99.9%

Sigma-Aldrich

Metanolo, suitable for HPLC, gradient grade, suitable as ACS-grade LC reagent, ≥99.9%

Sigma-Aldrich

Metanolo, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8% (GC)

Sigma-Aldrich

Metanolo, Laboratory Reagent, ≥99.6%

Sigma-Aldrich

Etanolo, ACS reagent, prima fine spirit, without additive, F15 o¹

Sigma-Aldrich

Etanolo, purum, absolute ethanol, denaturated with 4.8% isopropanol, A15 IPA¹, ≥99.8% (based on denaturant-free substance)

Sigma-Aldrich

Ammonio acetato, for molecular biology, ≥98%

Sigma-Aldrich

Metanolo, ACS spectrophotometric grade, ≥99.9%

Sigma-Aldrich

Acetonitrile, suitable for HPLC-GC, ≥99.8% (GC)

Sigma-Aldrich

Ammonium acetate solution, for molecular biology, 7.5 M

Sigma-Aldrich

Metanolo, ACS reagent, ≥99.8%

Sigma-Aldrich

Metanolo, BioReagent, ≥99.93%

Sigma-Aldrich

Metanolo, Absolute - Acetone free

USP

Metanolo, United States Pharmacopeia (USP) Reference Standard

Sigma-Aldrich

Acetonitrile, biotech. grade, ≥99.93%

Sigma-Aldrich

Ammonio acetato, 99.999% trace metals basis

Sigma-Aldrich

Ethyl alcohol, Pure, 190 proof, ACS spectrophotometric grade, 95.0%