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Documenti fondamentali

577515-U

Supelco

Colonna per HPLC Discovery® Cyano

5 μm particle size, L × I.D. 2 cm × 3 mm

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About This Item

Codice UNSPSC:
41115700
eCl@ss:
32110501

Materiali

stainless steel column

agenzia

suitable for USP L10

Nome Commerciale

Discovery®

Caratteristiche

endcapped

Produttore/marchio commerciale

Discovery®

Confezionamento

1 ea of

Grado di funzionalizzazione

4.5% Carbon loading

Parametri

≤70 °C temp. range
400 bar pressure (5801 psi)

tecniche

HPLC: suitable
LC/MS: suitable

Lungh. × D.I.

2 cm × 3 mm

Area superficiale

200 m2/g

Copertura della superficie

3.5 μmol/m2

Impurezze

<10 ppm metals

Matrice

silica gel, high purity, spherical base material
fully porous particle

Gruppo funzionale matrice

cyano phase

Dimensione particelle

5 μm

Dimensione pori

180 Å

Intervallo di pH d’impiego

2-8

applicazioni

food and beverages

Tecnica di separazione

hydrophilic interaction (HILIC)
normal phase
reversed phase

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Caratteristiche e vantaggi

  • Bassa idrofobia per una rapida eluizione degli analiti idrofobi
  • Forma di picco e ritenzione di analiti fortemente basici eccellenti
  • Ritenzione di analiti polari
  • Selettività unica
  • Ritenzione significativamente minore rispetto al C18 (di solito necessita di una percentuale inferiore di fase mobile organica)
  • Separazioni LC-MS stabili e a basso bleeding.
  • Compatibile con fasi organiche molto acquose

Prodotti consigliati

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Note legali

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

Lot/Batch Number

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Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
Christophe Morisseau et al.
Analytical biochemistry, 414(1), 154-162 (2011-03-05)
The microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of numerous xenobiotics. In addition, it has a potential role in sexual development and bile acid transport, and it is associated with a number of diseases such as
Srdan Verstovsek et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(3), 788-796 (2008-02-05)
The discovery of an activating somatic mutation in codon 617 of the gene encoding the Janus kinase (JAK)-2 (JAK2 V617F) in patients with myeloproliferative disorders has opened new avenues for the development of targeted therapies for these malignancies. However, no
K Umekawa et al.
Japanese journal of pharmacology, 84(1), 7-15 (2000-10-24)
We describe the pharmacological characteristics of SM-19712 (4-chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl] benzenesulfonamide, monosodium salt). SM-19712 inhibited endothelin converting enzyme (ECE) solubilized from rat lung microsomes with an IC50 value of 42 nM and, at 10 - 100 microM, had no effect on other
Ye Ding et al.
Chemical communications (Cambridge, England), 47(33), 9495-9497 (2011-07-19)
A novel and facile DDQ-mediated dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones is described. The formation of lactones proceeds by a radical ion mechanism, which has been established by DPPH˙-mediated chemical identification, ESR spectroscopy

Contenuto correlato

Discovery® HPLC Columns for Fast LC-MS Analysis. The Discovery LC-MS line offers short length columns for fast LC-MS analysis that are rugged and dependable. Supelco offers a robust product that withstands column shock due to fast gradient turnaround times.

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