X7375

Xantina

≥99%

• Sinonimo/i: 2,6-diidrossipurina
• Formula empirica (notazione di Hill): C₅H₄N₄O₂
• Numero CAS: 69-89-6
• Peso molecolare: 152.11
• Beilstein: 8733
• Numero CE: 200-718-6
• Numero MDL: MFCD00078453
• Codice UNSPSC: 41106305
• ID PubChem: 24902156
• NACRES: NA.51

Proprietà

• Origine biologica: synthetic (organic)
• Livello qualitativo: 300
• Saggio: ≥99%
• Stato: powder
• Solubilità: 1 M NaOH: soluble 50 mg/mL, clear to slightly hazy; NH₄OH: freely soluble; NaOH: freely soluble
• Stringa SMILE: O=C1NC(=O)c2nc[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11); LRFVTYWOQMYALW-UHFFFAOYSA-N

Descrizione

Descrizione generale

Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid.[1] Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.[2]

Applicazioni

Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay.[3] It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells[4] and algal cells.[5]

Azioni biochim/fisiol

A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples.[1] Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine.[6]

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves