T1428
apo-Transferrin bovine
BioReagent, suitable for cell culture, ≥98%
Sinonimo/i:
Human serotransferrin
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50 MG
CHF 108.00
100 MG
CHF 160.00
500 MG
CHF 539.00
5 G
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10 G
Chiedi
Scegli un formato
Cambia visualizzazione
50 MG
CHF 108.00
100 MG
CHF 160.00
500 MG
CHF 539.00
5 G
Chiedi
10 G
Chiedi
About This Item
Prodotti consigliati
Origine biologica
bovine
Livello qualitativo
Nome Commerciale
BioReagent
Saggio
≥98%
Stato
powder
tecniche
cell culture | mammalian: suitable
Impurezze
iron, essentially free
Solubilità
H2O: 10 mg/mL
N° accesso UniProt
Temperatura di conservazione
2-8°C
Informazioni sul gene
bovine ... TF(280705)
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Descrizione generale
apo-Transferrin is an iron-free form of transferrin that is present in circulation.[1]
Applicazioni
All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.
Azioni biochim/fisiol
apo-Transferrin (apoTf) aids in preventing iron accumulation in tissues, especially in non-transfusion dependent β-thalassemia.[6]
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I clienti hanno visto anche
Monique P Gelderman et al.
Haematologica, 100(5), 611-622 (2015-01-27)
Intermediate beta-thalassemia has a broad spectrum of sequelae and affected subjects may require occasional blood transfusions over their lifetime to correct anemia. Iron overload in intermediate beta-thalassemia results from a paradoxical intestinal absorption, iron release from macrophages and hepatocytes, and
Keita Abe et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 63(1-2), 154-156 (2008-04-05)
We have investigated the mechanism of manganese ion uptake by apo-transferrin using a capillary electrophoresis method, and obtained clear evidence that oxidation state +3 and the binuclear unit of a manganese chelate are essential factors for the facile uptake by
Einar Vargas-Bello-Pérez et al.
Animal nutrition (Zhongguo xu mu shou yi xue hui), 5(2), 202-208 (2019-06-14)
The objective of this study was to determine how cytosolic triacylglycerols (TAG) are stored in mammary cells and whether this depends on the individual chemical configuration of fatty acids (FA). This objective was accomplished by addition of different FA to
Shanshan Li et al.
Journal of animal science and biotechnology, 7, 44-44 (2016-08-06)
The objective of this study was to study how changing the ratio of Lys to Thr, Lys to His, and Lys to Val affects the expression of lipogenic genes and microRNA (miRNA) in bovine mammary epithelial cells. Triplicate cultures with
Function and therapeutic development of apotransferrin.
Jaakko Parkkinen et al.
Vox sanguinis, 83 Suppl 1, 321-326 (2003-03-06)
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