SML2369

Tipelukast

≥98% (HPLC)

• Sinonimo/i: 4-[6-Acetyl-3-[3-[(4-acetyl-3-hydroxy-2-propylphenyl)thio]propoxy]-2-propylphenoxy]butanoic acid, KCA-757, MN-001
• Formula empirica (notazione di Hill): C₂₉H₃₈O₇S
• Numero CAS: 125961-82-2
• Peso molecolare: 530.67
• Numero MDL: MFCD00886138
• Codice UNSPSC: 51111800
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: powder
• Condizioni di stoccaggio: desiccated
• Colore: white to beige
• Solubilità: DMSO: 2 mg/mL, clear
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CCCC1=C(SCCCOC2=C(CCC)C(OCCCC(O)=O)=C(C(C)=O)C=C2)C=CC(C(C)=O)=C1O
• InChI: 1S/C29H38O7S/c1-5-9-23-25(14-12-22(20(4)31)29(23)36-16-7-11-27(32)33)35-17-8-18-37-26-15-13-21(19(3)30)28(34)24(26)10-6-2/h12-15,34H,5-11,16-18H2,1-4H3,(H,32,33); KPWYNAGOBXLMSE-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

Antifibrotic and anti-inflammatory Leukotriene D4 (LTD4) receptor antagonist and inhibitor of 5-lipoxygenase (5-LO) and phosphodiesterases PDE3 and PDE4.

Tipelukast is a Leukotriene D4 (LTD4) receptor antagonist and an inhibitor of 5-lipoxygenase (5-LO) and also phosphodiesterases PDE3 and PDE4. It has been found to have antifibrotic and anti-inflammatory activity. Tipelukast has been investigated as a possible treatment for nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable