SML0396

Tafenoquine succinate

≥95% (HPLC)

• Sinonimo/i: N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine, SB-252263, WR 238605
• Formula empirica (notazione di Hill): C₂₄H₂₈F₃N₃O₃ · C₄H₆O₄
• Numero CAS: 106635-81-8
• Peso molecolare: 581.58
• Numero MDL: MFCD00892249
• Codice UNSPSC: 12352200
• ID PubChem: 329825392
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95% (HPLC)
• Stato: powder
• Condizioni di stoccaggio: desiccated
• Colore: white to beige
• Solubilità: DMSO: 5 mg/mL (clear solution)
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
• InChI: 1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8); CQBKFGJRAOXYIP-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

Tafenoquine has been generally generated for oral administration and drug absorption increases when taken along with food.[1] It is known to possess a longer half life.[2]

Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.

Tafenoquine is an antimalarial.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable