SML0396

Tafenoquine succinate

≥95% (HPLC), primaquine analog, powder

• Sinonimo/i: N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine, SB-252263, WR 238605
• Formula empirica (notazione di Hill): C₂₄H₂₈F₃N₃O₃ · C₄H₆O₄
• Numero CAS: 106635-81-8
• Peso molecolare: 581.58
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825392
• NACRES: NA.77
• MDL number: MFCD00892249
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated

Proprietà

• Nome del prodotto: Tafenoquine succinate, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 5 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
• InChI: 1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)
• InChI key: CQBKFGJRAOXYIP-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.

Tafenoquine is an antimalarial.

Tafenoquine has been generally generated for oral administration and drug absorption increases when taken along with food. It is known to possess a longer half life.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable