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RAB1351
Human CD74 ELISA
for serum, plasma and cell culture supernatants
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96 WELLS
CHF 594.00
CHF 594.00
Spedizione prevista il23 aprile 2025
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Cambia visualizzazione
96 WELLS
CHF 594.00
About This Item
Codice UNSPSC:
41116158
NACRES:
NA.32
CHF 594.00
Spedizione prevista il23 aprile 2025
Prodotti consigliati
Reattività contro le specie
human
Confezionamento
kit of 96 wells (12 strips x 8 wells)
tecniche
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.1 ng/mL
standard curve range: 0.102-25 ng/mL
Metodo di rivelazione
colorimetric
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... CD74(972)
Descrizione generale
The CD74 (HLA-DR (human leukocyte antigen – antigen D related) antigens-associated invariant chain) gene encodes for a type II transmembrane protein and is expressed by antigen presenting cells such as monocytes, B cells, macrophages and dendritic cells.[1][2] The CD74 gene is mapped to human chromosome 5q33.1.[3]
Applicazioni
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Azioni biochim/fisiol
CD74 (HLA-DR (human leukocyte antigen – antigen D related) antigens-associated invariant chain) is part of major histocompatibility complex (MHC) class II and its function is associated with antigen presentation. Upregulation of the CD74 gene is observed cancer including breast cancer and it is known to promote to metastasis.[4] CD74 also serves as a cytokine receptor in immune and epithelial cells. It induces cellular processes such as cell proliferation, migration and survival pathways.[5]
Altre note
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Met. Corr. 1
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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CD74 and intratumoral immune response in breast cancer.
Wang Z Q, et al.
Oncotarget, 8(8), 12664-12664 (2017)
Van?den Berghe?s 5q?syndrome in 2008.
Mohamedali A and Mufti G J
British Journal of Haematology, 144(2), 157-168 (2009)
Gabriela Athziri Sánchez-Zuno et al.
Journal of clinical medicine, 11(1) (2022-01-12)
Macrophage migration inhibitory factor (MIF) significantly contributes to rheumatoid arthritis (RA) pathogenesis. We aimed to evaluate the canonical (CD74/CD44) and non-canonical MIF receptors (CXCR2,4 and 7) expression and sCD74 to establish their association with RA clinical activity according to DAS28-ESR.
GSK-3?-mediated fatty acid synthesis enhances epithelial to mesenchymal transition of TLR4-activated colorectal cancer cells through regulation of TAp63.
Park G B, et al.
International Journal of Oncology, 49(5), 2163-2172 (2016)
Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74.
Meza-Romero R, et al.
Cytokine, 88, 62-70 (2016)
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Hi, can you tell me what are the volume of all reagents at Human CD74 ELISA (RAB1351)? Thanks a lot!
1 answer
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