MAK192
Cholesterol Efflux Assay Kit
Sufficient for 100 Fluorometric tests
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About This Item
Codice UNSPSC:
12161503
Prodotti consigliati
applicazioni
cosmetics
food and beverages
pharmaceutical
Metodo di rivelazione
fluorometric
Malattie correlate
cardiovascular diseases
Temperatura di conservazione
−20°C
Descrizione generale
Reverse Cholesterol Transport (RCT) is the mechanism by which the peripheral lipid burden is reduced by transport to liver and its fecal excretion. The first important step in RCT is the cholesterol efflux from macrophage-derived foam cells present in atherosclerotic plaques. The cholesterol efflux is critical for the maintenance of net cholesterol balance in arterial walls and in the reduction of proinflammatory responses triggered by lipid-laden macrophages.
Applicazioni
Cholesterol Efflux Assay Kit has been used in cholesterol efflux assay.
Caratteristiche e vantaggi
Compatible with high-throughput handling systems.
Compatibilità
Suitable for the determination of cholesterol efflux in cells.
Principio
The Cholesterol Efflux Assay Kit is a high-throughput screening assay that measures cholesterol efflux in cells using fluorescent-labeled cholesterol (λEx = 482 nm/ λEm = 515 nm). It is suitable for serum, isolated, or recombinant lipoprotein samples. It may also be used to screen small molecules for their effect on cholesterol efflux and therefore, may be a valuable tool in drug discovery programs.
Solo come componenti del kit
N° Catalogo
Descrizione
- Labeling Reagent
- Equilibration Buffer
- Reagent A
- Reagent B
- Cell Lysis Buffer
- Positive Control
- Serum Treatment Reagent
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2
Codice della classe di stoccaggio
10 - Combustible liquids
Punto d’infiammabilità (°F)
188.6 °F - closed cup
Punto d’infiammabilità (°C)
87 °C - closed cup
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