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K4769

Sigma-Aldrich

Kojibiose

≥98% (HPLC)

Sinonimo/i:

α-D-Glc-(1→2)-D-Glc, 2-O-α-D-Glucopyranosyl-D-glucose

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About This Item

Formula empirica (notazione di Hill):
C12H22O11
Numero CAS:
Peso molecolare:
342.30
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.25

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Saggio

≥98% (HPLC)

Stato

powder

tecniche

HPLC: suitable

Colore

white to off-white

Solubilità

water: 5 mg/mL, clear, colorless

Temperatura di conservazione

−20°C

Stringa SMILE

OCC(O)C(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(17)8(18)5(2-14)22-12-11(21)10(20)9(19)6(3-15)23-12/h2,4-13,15-21H,1,3H2
PZDOWFGHCNHPQD-UHFFFAOYSA-N

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Applicazioni

Kojibiose, a disaccharide product of glucose caramelization and an inhibitor of plant glucosidase I, may be used to help identify and characterize glucosidase I enzymes involved in terminal deglycosylation of high-mannose oligosaccharides.[1] Kojibiose may be used as a substrate to study the biological species, enzymes and catabolic processes that catabolize it as an energy source. Kojibiose may be used to identify, differentiate and characterize kojibiose phosphorylase(s) (KP).[2]

Azioni biochim/fisiol

Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from (Glc)3(Man)9(GlcNAc)2.
Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from the high-mannose oligosaccharide (Glc)3(Man)9(GlcNAc)2, either from the free oligosaccharide or from the oligosaccharide attached to a protein via N-linkage.

Altre note

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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The FEBS journal, 281(3), 778-786 (2013-11-22)
Glycoside hydrolase (GH) family 65 contains phosphorylases acting on maltose (Glc-α1,4-Glc), kojibiose (Glc-α1,2-Glc), trehalose (Glc-α1,α1,-Glc), and nigerose (Glc-α1,3-Glc). These phosphorylases can efficiently catalyze the reverse reactions with high specificities, and thus can be applied to the practical synthesis of α-glucosyl
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Journal of bacteriology, 196(5), 1122-1131 (2014-01-07)
A unique gene cluster responsible for kojibiose utilization was identified in the genome of Pyrococcus sp. strain ST04. The proteins it encodes hydrolyze kojibiose, a disaccharide product of glucose caramelization, and form glucose-6-phosphate (G6P) in two steps. Heterologous expression of
Jarred Yasuhara-Bell et al.
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Rathayibacter toxicus is a Gram-positive, nematode-vectored bacterium that infects several grass species in the family Poaceae. Unique in its genus, R. toxicus has the smallest genome, possesses a complete CRISPR-Cas system, a vancomycin-resistance cassette, produces tunicamycin, a corynetoxin responsible for
Synthesis of linear oligosaccharides: L-glycero-alpha-D-manno-heptopyranosyl derivatives of allyl alpha-glycosides of D-glucose, kojibiose, and 3-O-alpha-kojibiosyl-D-glucose, substrates for synthetic antigens.
S A Nepogod'ev et al.
Carbohydrate research, 254, 43-60 (1994-02-17)
S Ogawa et al.
Carbohydrate research, 307(1-2), 83-95 (1998-07-11)
Two kojibiose-type pseudo-disaccharides and a trisaccharide, containing a 5-amino-1,2,3,4-cyclopentanetetrol derivative or valienamine, linked by way of nitrogen bridges to the sugar residues, have been designed and synthesized as processing alpha-glucosidase I inhibitors. Synthesis of the pseudo-disaccharides was carried out starting

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