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I2386

Sigma-Aldrich

Anti-Human IgM (μ-chain specific) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-IgM produced in Goat, Goat Anti-Human IgM, IgM Detection Antibody

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1 ML
CHF 216.00

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1 ML
CHF 216.00

About This Item

Numero MDL:
MFCD00162459
Codice UNSPSC:
12352203
NACRES:
NA.46

CHF 216.00

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Origine biologica

goat

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

tecniche

indirect ELISA: 1:20,000-1:40,000

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

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Categorie correlate

Descrizione generale

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.

Applicazioni

Anti-Human IgM (μ-chain specific) antibody produced in goat has been used in enzyme linked immunosorbent assay (ELISA).

Azioni biochim/fisiol

Immunoglobulin M (IgM) antibodies are the primary ones to be produced in response to antigen. They bind with low affinity but exhibit a broad specificity to a variety of antigens. IgM constitutes 15% of adult immunoglobulins. IgM is important for fetal and neonatal host defenses for several reasons. IgM molecule efficiently activates classical pathway of complement. Its pentameric structure helps in accomodating multivalent ligand binding. IgM has a prominent role in clearance of invading microorganisms from serum.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificati d'analisi (COA)

Lot/Batch Number
0000423584
0000423584
0000386119
0000386119
0000358461

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Anti-protein immunoglobulin M responses to pneumococcus are not associated with aging
German EL, et al.
Pneumonia (Nathan Qld.), 10(1), 5-5 (2018)
J Ollila et al.
Genes and immunity, 4(5), 343-350 (2003-07-09)
The development of adaptive immunity and responses to foreign molecules and organisms relies on the highly regulated production of hundreds of proteins. B-cell maturation, from committed progenitors to terminally differentiated plasma cells, is a multistep process that requires the ordered
Fredy Brice Nemg Simo et al.
Intervirology, 61(6), 265-271 (2019-05-03)
On May 2017, a case of dengue serotype 1 was detected and confirmed through routine surveillance in a traveler returning from Kribi, a seaside town of Southern Cameroon. This study aimed at confirming the circulation of dengue virus (DENV) in
Johannes U Ammann et al.
Current protocols in protein science, 75, 19-19 (2014-02-11)
Discovery of binding partners for immunoglobulin molecules expressed by cells of the immune system is an important topic of current research. However, many ligand-receptor interactions are of low affinity, and hence detection is refractory to most established protocols. We evaluated
Yang Li et al.
Cell reports, 34(13), 108915-108915 (2021-03-25)
To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a systematic way. We generate a linear epitope landscape of the Spike protein
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