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H7166

Sigma-Aldrich

IL-3 human

HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

Sinonimo/i:

Interleukin-3 human, IL-3

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10 μG
CHF 466.00

CHF 466.00

Spedizione prevista il28 marzo 2025

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10 μG
CHF 466.00

About This Item

Numero MDL:
MFCD00147276
Codice UNSPSC:
12352202
NACRES:
NA.77

CHF 466.00

Spedizione prevista il28 marzo 2025

Nome del prodotto

Interleukin-3 human, IL-3, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

Origine biologica

human

Livello qualitativo

100

Ricombinante

expressed in HEK 293 cells

Saggio

>95% (SDS-PAGE)

Stato

lyophilized powder

Potenza

≤2 ng/mL EC50

Qualità

endotoxin tested

PM

dimer 17-45 kDa (glycosylated)

Confezionamento

pkg of 10 μg

Produttore/marchio commerciale

HumanZyme

tecniche

cell culture | mammalian: suitable

Impurezze

<1 EU/μg

N° accesso UniProt

P08700

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... IL3(3562)

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Categorie correlate

Azioni biochim/fisiol

Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.

Stato fisico

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

Nota sulla preparazione

HumanKine Interleukin-3 (IL-3), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 17-45 kDa due to glycosylation, which is absent when this cytokine is expressed in E. coli. Production in human HEK 293 cells offers authentic glycosylation which contributes to stability in cell growth media and other applications.

Risultati analitici

The activity was determined by the dosedependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Note legali

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCV6287
MKCS7822
MKCQ9909
MKCP9009
MKCL9853

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