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G3126

Sigma-Aldrich

L-glutammina

≥99% (HPLC), ReagentPlus®

Sinonimo/i:

5-ammide dell’acido L-glutammico, Acido (S)-2,5-diammino-5-ossopentanoico, Levoglutamide

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100 G
CHF 155.00
250 G
CHF 311.00
500 G
CHF 793.00
1 KG
CHF 1’250.00

CHF 155.00


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Cambia visualizzazione
100 G
CHF 155.00
250 G
CHF 311.00
500 G
CHF 793.00
1 KG
CHF 1’250.00

About This Item

Formula condensata:
H2NCOCH2CH2CH(NH2)CO2H
Numero CAS:
Peso molecolare:
146.14
Beilstein:
1723797
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

CHF 155.00


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Nome del prodotto

L-glutammina, ReagentPlus®, ≥99% (HPLC)

Livello qualitativo

Nome Commerciale

ReagentPlus®

Saggio

≥99% (HPLC)

Stato

powder

Impurezze

≤0.2% free ammonia.
~0.5% Glutamic acid

Colore

white to off-white

Punto di fusione

185 °C (dec.) (lit.)

Solubilità

1 M HCl: 50 mg/mL, clear to slightly hazy, colorless

Cationi in tracce

<0.2% (Ammonia (NH3))

applicazioni

cell analysis
peptide synthesis

Gruppo funzionale

amide

Temperatura di conservazione

room temp

Stringa SMILE

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
ZDXPYRJPNDTMRX-VKHMYHEASA-N

Informazioni sul gene

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Descrizione generale

L-Glutamine is a versatile amino acid that plays an essential role in various metabolic processes within the human body. This non-essential amino acid is naturally abundant and contributes significantly to several vital functions. One of its primary functions is acting as the primary carrier of nitrogen in the body. It serves as the transport vehicle for nitrogen, which is a fundamental building block for many biological processes. Additionally, L-Glutamine is a major energy source for numerous types of cells, ensuring they have the energy they need to function optimally.

Moreover, L-Glutamine is essential for maintaining a delicate balance of ammonia in the body. This balance is crucial for preventing toxic ammonia levels. This amino acid facilitates the conversion of glutamic acid to glutamine, a process central to ammonia regulation. L-Glutamine is not only involved in nitrogen transport and energy production but also serves as a key player in various metabolic pathways. It participates in the biosynthesis of proteins, similar to other amino acids. Furthermore, it plays a significant role in the synthesis of urea and purines, vital components for nucleic acid production. L-Glutamine is also a vital resource for generating cellular energy, working closely with glucose for this purpose.

Another essential function of L-Glutamine is its contribution to nitrogen donation for multiple anabolic processes. These processes are vital for building crucial molecules, including purines, which are crucial for DNA production. This amino acid also provides carbon, replenishing the citric acid cycle, a central process in energy production within cells. L-Glutamine is a critical amino acid, acting as a nitrogen carrier, energy source, and contributing to protein synthesis and ammonia regulation. Its versatile functions make it a molecule of significant interest in the fields of cell biology, biochemical research, and metabolomics investigations.

Applicazioni

L-Glutamine has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.[1]It has also been used to study non-enzymatic gluconeogenesis.[2]

Azioni biochim/fisiol

L-glutamine is the most abundant amino acid in the body. It is essential for the synthesis of L-asparagine.[3][4] L-glutamic acid aids the incorporation of NH4+ into biomolecules.[5]
La L-glutammina è un amminoacido essenziale oltre che un componente fondamentale dei terreni di coltura e costituisce un′importante fonte di energia per le cellule coltivate. La L-glutammina è molto stabile in forma di polvere secca e di soluzione congelata. Tuttavia, nei terreni liquidi e nelle soluzioni madri, la L-glutammina si degrada con relativa rapidità. Per una resa ottimale delle cellule è generalmente necessaria l′integrazione dei terreni di coltura con la L-glutammina prima dell′uso.

Caratteristiche e vantaggi

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

Altre note

For additional information on our range of Biochemicals, please complete this form.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

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Advances in Food and Nutrition Research, 58-58 (1917)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature, 1-36 (2017)
The Natural Health Dictionary: Your comprehensive A-to Z guide for healing with herbs, nutrition, supplements, and secret remedies (2011)
Lehninger Principles of Biochemistry Edition 4th (2005)
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Messner CB
Proceedings of the National Academy of Sciences of the USA, 114(28), 7403-7407 (2017)

Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. Is the molecular weight of L-Glutamine 146.14 or 146.15? The label information changed.

    1 answer
    1. Based on a molecular formula of C5H10N2O3, the molecular weight to seven significant figures is 146.1456. Over the years, this value may have been reported in Sigma-Aldrich documentation or on labels as either 146.15 (by rounding up) or 146.14 (by truncation). The material itself has not changed.

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