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G0902

Sigma-Aldrich

Ginsenoside-Rc from Panax ginseng (Korean ginseng) root

triterpenoid saponin, ≥98% (HPLC)

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5 MG
CHF 479.00

CHF 479.00

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5 MG
CHF 479.00

About This Item

Formula empirica (notazione di Hill):
C53H90O22
Numero CAS:
11021-14-0
Peso molecolare:
1079.27
Numero CE:
234-253-5
Numero MDL:
MFCD00133368
Codice UNSPSC:
12352201
ID PubChem:
24895029
NACRES:
NA.25

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Origine biologica

plant root (Panax ginseng)

Livello qualitativo

200

Saggio

≥98% (HPLC)

Stato

powder

tecniche

HPLC: suitable

Temperatura di conservazione

2-8°C

Stringa SMILE

C\C(C)=C\CCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C

InChI

1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-68-45-41(65)36(60)28(21-56)69-45)24-11-16-52(7)33(24)25(57)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)35(59)27(20-55)71-48)74-46-42(66)38(62)34(58)26(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3
JDCPEKQWFDWQLI-UHFFFAOYSA-N

Azioni biochim/fisiol

Ginsenoside-Rc exhibits anti-proliferative effects on human breast cancer cell lines and can induce expreβion of the leucine-zipper transcription factor c-fos. [1]
Triterpene saponin found in ginseng.

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Consigli di prudenza

P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
0000321052
0000294750
0000321052
0000294750
087M4122V

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Sigma-Aldrich

G7253

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Ginsenoside Rg3 ≥98% (HPLC)

Sigma-Aldrich

SML0184

Ginsenoside Rg3

Ginsenoside Re primary reference standard

03000590

Ginsenoside Re

Ginsenoside Compound K ≥96% (HPLC)

Sigma-Aldrich

SMB00348

Ginsenoside Compound K

Ginsenoside Rb1 European Pharmacopoeia (EP) Reference Standard

Y0001347

Ginsenoside Rb1

vibrant-m

05115001

Panax ginseng extract

Yang Chu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 919-920, 75-78 (2013-02-16)
Ginsenoside Rc (GRc) is a potential pharmacologically active ingredient isolated from ginseng (Panax ginseng C.A. Meyer, Araliaceae). A simple, rapid and sensitive method for determination of GRc in rat plasma was developed based on liquid chromatography-tandem mass spectrometry (LC-MS/MS). The
Osamu Morinaga et al.
Glycobiology, 15(10), 1061-1066 (2005-06-24)
A method has been devised for the chromatographic resolution of glucosidic compounds, ginseng saponins, on polyethersulphone (PES) membrane. The method results in good resolution and quantitative immunoassay for ginsenoside Rb1 (G-Rb1), G-Rc, and G-Rd in crude extracts of various ginsengs.
Young Joo Lee et al.
Archives of pharmacal research, 26(1), 53-57 (2003-02-06)
We have found that ginsenoside Rc and Re induce c-fos in MCF-7 human breast carcinoma cells at both the mRNA and protein levels. However, neither ginsenoside activated the expression of reporter gene under the control of AP-1/TPA response elements. We
T B Ng et al.
Journal of ethnopharmacology, 16(2-3), 191-199 (1986-06-01)
Ginsenosides Rb2, Rc and Rg1 suppressed corticotropin-induced, dibutyryl cyclic AMP-induced and epinephrine-induced lipolysis with the relative potencies Rb2 greater than Rc greater than Rg1. The inhibition of corticotropin-induced lipolysis by ginsenoside Rg1 could not be overcome by increasing the dose
Y Han et al.
Journal of applied microbiology, 109(3), 792-798 (2010-03-27)
This study examined the transformation pathways of ginsenosides G-Rb(1) , G-Rb(3) , and G-Rc by the fungus Fusarium sacchari. Ginsenosides G-Rb(1) , G-Rb(3) and G-Rc were isolated from leaves of Radix notoginseng, and their structural identification was confirmed using NMR.
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application for HPLC

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