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C2650

Sigma-Aldrich

5-Cholenic acid-3β-ol

≥98%

Sinonimo/i:

3β-Hydroxy-5-cholen-24-oic acid

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About This Item

Formula empirica (notazione di Hill):
C24H38O3
Numero CAS:
Peso molecolare:
374.56
Numero MDL:
Codice UNSPSC:
12352211
ID PubChem:

Saggio

≥98%

Stringa SMILE

C[C@@H](CCC(O)=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C

InChI

1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h5,15,17-21,25H,4,6-14H2,1-3H3,(H,26,27)
HIAJCGFYHIANNA-UHFFFAOYSA-N

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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M Tohma et al.
Steroids, 44(1), 47-55 (1984-07-01)
The glycine conjugate of 3 beta-hydroxy-5-cholen-24-oic acid and its sulfate labeled with deuterium at the C-2, -4, and -23 positions were synthesized. A highly sensitive and specific quantitative assay of the bile acid has been developed by selected ion monitoring
L Riello et al.
Journal of pediatric gastroenterology and nutrition, 50(6), 655-660 (2010-04-20)
3beta-Hydroxy-Delta 5-C27-steroid dehydrogenase/isomerase deficiency is a bile acid synthesis defect responsive to primary bile acids. We reviewed its clinical features and response to treatment with a mixture of ursodeoxycholic (UDCA) and chenodeoxycholic acid (CDCA) to titrate the dose of supplements
Y Yamato et al.
Biology of the neonate, 80(1), 19-25 (2001-07-28)
To elucidate the urinary concentration of total bile acids after birth and the profile of the usual and unusual urinary bile acids, especially 3beta-hydroxy-5-cholen-24-oic acid (Delta(5)-3beta-ol), we measured the concentrations of 13 bile acids in the urine from preterm infants
R E Kane et al.
Journal of pediatric gastroenterology and nutrition, 12(2), 260-268 (1991-02-01)
Bile salt sulfotransferase (BSS) activity for the fetal bile acid, 3 beta-hydroxy-5-cholenoate, was first detected in the fetus at 18-19 days of gestation and was twofold greater than for glycolithocholate. The near-term (20-21 days of gestation) and newborn pup BSS
E Kok et al.
The Journal of biological chemistry, 256(12), 6155-6159 (1981-06-25)
Synthesis of 3 beta-hydroxy-5-[1,2-3H]cholenoic acid has permitted a study of its metabolism in bile-fistula hamsters that received the compound by intravenous infusion. Metabolites in bile were identified by reverse isotope dilution after their complete resolution by high pressure liquid chromatography

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