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B7929

Sigma-Aldrich

Anti-Bim antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-BOD

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About This Item

Numero MDL:
MFCD02095895
Codice UNSPSC:
12352203

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 23 kDa

Reattività contro le specie

human, rat, mouse

tecniche

immunohistochemistry: 20 μg/mL using human skin cancer cells
microarray: suitable
western blot: 1 μg/mL using A549 or K562 whole cell lysates

N° accesso UniProt

O43521

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... BCL2L11(10018)
mouse ... Bcl2l11(12125)
rat ... Bcl2l11(64547)

Immunogeno

synthetic peptide corresponding to amino acids 22-40 of human Bim (BOD). This sequence is identical in mouse and contains only one amino acid substitution in rat.

Stato fisico

Solution in phosphate buffered saline containing 0.02% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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P Geserick et al.
Cell death & disease, 5, e1412-e1412 (2014-09-12)
Tumour progression and therapy resistance in squamous cell carcinoma of the skin (SCC) is strongly associated with resistance to intrinsic mitochondrial apoptosis. We thus investigated the role of various anti-apoptotic Bcl-2 proteins for apoptosis protection in SCC using the BH3
Violeta Gómez-Vicente et al.
The European journal of neuroscience, 24(4), 981-990 (2006-08-26)
Apoptosis of photoreceptor cells in the early postnatal period is a normal feature of mammalian retinal development. The role of mitochondria and caspases in the process has been well established; however, the identification of key apoptotic mediators still remains elusive.
Nina Stojcheva et al.
Oncotarget, 7(11), 12937-12950 (2016-02-18)
Glioblastoma is the most aggressive brain tumor in adults with a median survival below 12 months in population-based studies. The main reason for tumor recurrence and progression is constitutive or acquired resistance to the standard of care of surgical resection
Laura Elisa Buitrago-Molina et al.
Cellular and molecular gastroenterology and hepatology, 11(5), 1387-1404 (2021-01-24)
A coordinated stress and regenerative response is important after hepatocyte damage. Here, we investigate the phenotypes that result from genetic abrogation of individual components of the checkpoint kinase 2/transformation-related protein 53 (p53)/cyclin-dependent kinase inhibitor 1A (p21) pathway in a murine
Marc B Guerin et al.
Clinical & experimental ophthalmology, 39(3), 243-251 (2011-04-15)
This paper seeks to investigate differences between the neonatal and adult retinal ganglion cell populations to apoptotic death stimuli. DESIGN AND SAMPLES: In vitro and ex vivo paradigms involving P6 and P60 Sprague-Dawley rat retinal explants and retinal ganglion cells
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