B3313

Bicyclol

≥98% (HPLC)

• Sinonimo/i: 4, 4′-dimethoxy-2, 3, 2′, 3′-bis(methylenedioxy)-6-hydroxymethyl-6′-methoxy-carbonyl biphenyl
• Formula empirica (notazione di Hill): C₁₉H₁₈O₉
• Numero CAS: 118159-48-1
• Peso molecolare: 390.34
• Numero MDL: MFCD00889471
• Codice UNSPSC: 12352202
• ID PubChem: 329773215
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: powder
• Condizioni di stoccaggio: desiccated
• Colore: white to off-white
• Solubilità: DMSO: >10 mg/mL
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: COC(=O)c1cc(OC)c2OCOc2c1-c3c(CO)cc(OC)c4OCOc34
• InChI: 1S/C19H18O9/c1-22-11-4-9(6-20)13(17-15(11)25-7-27-17)14-10(19(21)24-3)5-12(23-2)16-18(14)28-8-26-16/h4-5,20H,6-8H2,1-3H3; KXMTXZACPVCDMH-UHFFFAOYSA-N

Descrizione

Descrizione generale

Bicyclol has anti-inflammatory properties and enhances the prognosis of kidney transplantation.[1] It is involved in the removal of reactive oxygen species and modulates cytokine secretion.[2]

Azioni biochim/fisiol

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C.

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. The drug appears to protect against liver injury in animals. Recently it was reported that bicyclol induce the expression of hepatic HSP27 and HSP70, and thus consequently inhibits the transcription factor NF-?B-mediated apoptosis and necrosis in liver tissue. It appears that bicyclol induces hepatic HSP27 and HSP70 expression through activating transcription of HSPs genes.

Informazioni sulla sicurezza

• Pittogrammi: GHS09
• Avvertenze: Warning
• Indicazioni di pericolo: H410
• Consigli di prudenza: P273 - P391 - P501
• Classi di pericolo: Aquatic Acute 1 - Aquatic Chronic 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves