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A6226

Sigma-Aldrich

AM251

>98% (HPLC), solid, cannabinoid receptor (CB1) antagonist

Sinonimo/i:

1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide

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About This Item

Formula empirica (notazione di Hill):
C22H21N4OCl2I
Numero CAS:
183232-66-8
Peso molecolare:
555.24
Numero MDL:
MFCD01861181
Codice UNSPSC:
12352200
ID PubChem:
24891069
NACRES:
NA.77

Nome del prodotto

AM251, >98% (HPLC), solid

Livello qualitativo

100

Saggio

>98% (HPLC)

Stato

solid

Colore

white

Solubilità

DMSO: >10 mg/mL
H2O: insoluble

Ideatore

Sanofi Aventis

Stringa SMILE

Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(I)cc3)C(=O)NN4CCCCC4

InChI

1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
BUZAJRPLUGXRAB-UHFFFAOYSA-N

Informazioni sul gene

mouse ... Cnr1(12801) , Cnr2(12802)
rat ... Cnr1(25248)

Applicazioni

AM251, a CB1 cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.

Azioni biochim/fisiol

AM251 is a CB1 cannabinoid receptor antagonist.

Caratteristiche e vantaggi

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Altre note

Salt content may vary.

Indicazioni di pericolo

H413

Consigli di prudenza

P273 - P501

Classi di pericolo

Aquatic Chronic 4

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
0000310720
0000310720
0000390807
0000390809
0000310714

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Sigma-Aldrich

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